TY - JOUR
T1 - Evaluation of risk factors for severe pneumonia in children
T2 - The pneumonia etiology research for child health study
AU - Wonodi, Chizoba B.
AU - Deloria-Knoll, Maria
AU - Feikin, Daniel R.
AU - Deluca, Andrea N.
AU - Driscoll, Amanda J.
AU - Moïsi, Jennifer C.
AU - Johnson, Hope L.
AU - Murdoch, David R.
AU - O'Brien, Katherine L.
AU - Levine, Orin S.
AU - Scott, J. Anthony G.
N1 - Funding Information:
Supplement sponsorship. This article was published as part of a supplement entitled ‘‘Pneumonia Etiology Research for Child Health,’’ sponsored by a grant from The Bill & Melinda Gates Foundation to the PERCH Project of Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland. Potential conflicts of interest. All authors: No reported conflicts.
Funding Information:
J. A. G. S. is supported by a clinical fellowship from The Wellcome Trust of Great Britain (number 081835).
Funding Information:
Financial support. This work was supported by grant 48968 from The Bill & Melinda Gates Foundation to the International Vaccine Access Center, Department of International Health, Johns Hopkins Bloomberg School of Public Health.
PY - 2012/4/1
Y1 - 2012/4/1
N2 - As a case-control study of etiology, the Pneumonia Etiology Research for Child Health (PERCH) project also provides an opportunity to assess the risk factors for severe pneumonia in hospitalized children at 7 sites. We identified relevant risk factors by literature review and iterative expert consultation. Decisions for inclusion in PERCH were based on comparability to published data, analytic plans, data collection costs and logistic feasibility, including interviewer time and subject fatigue. We aimed to standardize questions at all sites, but significant variation in the economic, cultural, and geographic characteristics of sites made it difficult to obtain this objective. Despite these challenges, the depth of the evaluation of multiple risk factors across the breadth of the PERCH sites should furnish new and valuable information about the major risk factors for childhood severe and very severe pneumonia, including risk factors for pneumonia caused by specific etiologies, in developing countries.
AB - As a case-control study of etiology, the Pneumonia Etiology Research for Child Health (PERCH) project also provides an opportunity to assess the risk factors for severe pneumonia in hospitalized children at 7 sites. We identified relevant risk factors by literature review and iterative expert consultation. Decisions for inclusion in PERCH were based on comparability to published data, analytic plans, data collection costs and logistic feasibility, including interviewer time and subject fatigue. We aimed to standardize questions at all sites, but significant variation in the economic, cultural, and geographic characteristics of sites made it difficult to obtain this objective. Despite these challenges, the depth of the evaluation of multiple risk factors across the breadth of the PERCH sites should furnish new and valuable information about the major risk factors for childhood severe and very severe pneumonia, including risk factors for pneumonia caused by specific etiologies, in developing countries.
UR - http://www.scopus.com/inward/record.url?scp=84858120473&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84858120473&partnerID=8YFLogxK
U2 - 10.1093/cid/cir1067
DO - 10.1093/cid/cir1067
M3 - Article
C2 - 22403226
AN - SCOPUS:84858120473
SN - 1058-4838
VL - 54
SP - S124-S131
JO - Clinical Infectious Diseases
JF - Clinical Infectious Diseases
IS - SUPPL. 2
ER -