Evaluation of movement speed and reaction time as predictors of all-cause mortality in men

E. Jeffrey Metter, Mathew Schrager, Luigi Ferrucci, Laura A. Talbot

Research output: Contribution to journalArticlepeer-review

28 Scopus citations


Muscle power is associated with mortality independent of strength, suggesting that movement speed and coordination convey health-related information. We hypothesized that movement speed is a marker of longevity. Our participants included 1196 men who performed a tapping and/or auditory simple (respond to a sound) and disjunctive (respond to a higher pitched sound) reaction-time tasks while participating in the Baltimore Longitudinal Study of Aging. Mortality was assessed over 40 years. Tapping time was associated with mortality (relative risk [RR] = 1.34 per minute, 95% confidence interval [CI], 1.05-1.70) adjusted for age, and persisted with adjustments for arm strength and power. Simple (RR = 1.17 per 100 ms, 95% CI, 1.03-1.32) and disjunctive (RR = 1.14 per 100 ms, 95% CI, 1.03-1.27) reaction times but not their difference (RR = 1.04 per 100 ms, 95% CI, 0.92-1.19) were associated with mortality after adjustments for age, neurological/psychiatric and neck/arm pain histories. Age-associated impairments in motor control systems but not the decision to move affects longevity.

Original languageEnglish (US)
Pages (from-to)840-846
Number of pages7
JournalJournals of Gerontology - Series A Biological Sciences and Medical Sciences
Issue number7
StatePublished - Jul 2005
Externally publishedYes

ASJC Scopus subject areas

  • Aging


Dive into the research topics of 'Evaluation of movement speed and reaction time as predictors of all-cause mortality in men'. Together they form a unique fingerprint.

Cite this