Abstract
Objectives: To investigate the cognitive effects of high-dose oral estrogen alone or in combination with oral methyltestosterone in postmenopausal women. Methods: Participants were tested with a randomized, double-blind design on the Identical Pictures, Cube Comparisons, Building Memory and Shape Memory tasks before and after 4 months of hormone treatment. Results: Women receiving estrogen and methyltestosterone maintained a steady level of performance on the Building Memory task, whereas those receiving estrogen alone showed a decrease in performance. Conclusions: These results indicate that the addition of testosterone to high-dose estrogen replacement exerts a protective effect on memory performance in postmenopausal women.
Original language | English (US) |
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Pages (from-to) | 150-155 |
Number of pages | 6 |
Journal | Hormone Research |
Volume | 58 |
Issue number | 3 |
DOIs | |
State | Published - 2002 |
Keywords
- Cognition
- Memory
- Menopause
- Perception
- Sex steroid hormones
ASJC Scopus subject areas
- Endocrinology, Diabetes and Metabolism
- Endocrinology