Evaluation of data acquisition geometries and strategies for myocardial SPECT imaging

Y. J. Qi, B. M.W. Tsui, K. J. Gilland, E. C. Frey, G. T. Gullberg

Research output: Contribution to conferencePaperpeer-review


This study evaluates myocardial SPECT images obtained from parallel-hole (PH) and fan-beam (FB) collimator geometries using both circular-orbit (CO) and noncircular-orbit (NCO) acquisitions. A newly developed 4D NURBS-based cardiac-torso (NCAT) was used to simulate the 99mTc-sestamibi uptakes in human torso with myocardial defects in the left ventricular (LV) wall. Projection data including the effects of attenuation, collimator-detector response and scatter were generated using SIMSET Monte Carlo simulations. A large number of photon histories were generated such that the projection data were close to noise-free. Poisson noise fluctuations were then added to simulate the count densities found in clinical data. Noise-free and noisy projection data were reconstructed using the iterative OS-EM reconstruction algorithm with attenuation compensation. The reconstructed images from noisy projection data show that the noise levels are lower for the FB as compared to the PH due to increase in detected counts. The NCO orbit provides improved defect contrast over the CO orbit in the noise-free reconstructed images as a result of improved spatial resolution. The improvements are more pronounced in the thinner phantom where NCO has larger eccentricity. Despite lower projection counts the NCO orbit shows the same noise level as the CO orbit in the attenuation corrected reconstruction images. The results from the Hotelling observer study show that FB collimator is superior to PH collimator in myocardial defect detection, but the NCO shows no statistical difference from the CO for either PH or FB collimator. In conclusion, our preliminary results indicate that combinations of collimator geometry and acquisition strategy provide different trade-offs between spatial resolution, contrast and noise in myocardial SPECT images. These trade-offs depend on the body shape of the patient.

Original languageEnglish (US)
Number of pages5
StatePublished - 2002
Externally publishedYes
Event2001 IEEE Nuclear Science Symposium Conference Record - San Diego, CA, United States
Duration: Nov 4 2001Nov 10 2001


Other2001 IEEE Nuclear Science Symposium Conference Record
Country/TerritoryUnited States
CitySan Diego, CA

ASJC Scopus subject areas

  • Radiation
  • Nuclear and High Energy Physics
  • Radiology Nuclear Medicine and imaging


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