TY - JOUR
T1 - Evaluation of choroidal layer thickness in central serous chorioretinopathy
AU - Hanumunthadu, Daren
AU - Van Dijk, Elon H.C.
AU - Dumpala, Sunila
AU - Rajesh, Bindu
AU - Jabeen, Ayesha
AU - Jabeen, Asiya
AU - Ansari, Momin
AU - Mehta, Pooja
AU - Shah, Shilpi
AU - Sarvaiya, Chintan
AU - Meyerle, Catherine
AU - Wu, Lihteh
AU - Banker, Alay
AU - Boon, Camiel J.
AU - Chhablani, Jay
N1 - Publisher Copyright:
© 2019 Journal of Ophthalmic and Vision Research.
PY - 2019/4/1
Y1 - 2019/4/1
N2 - Purpose: To evaluate medium and large choroidal vessel layer thickness (MCVT and LCVT, respectively) in eyes with acute and chronic central serous chorioretinopathy (CSC) in comparison with age-matched controls. Methods: The study included 96 eyes of 96 patients with CSC, including 53 eyes with acute CSC, 43 eyes with chronic CSC, and 30 eyes of 30 age-matched normal subjects. Manual measurements of subfoveal choroidal thickness (SFCT), MCVT, and LCVT at subfoveal and 750 μm nasal and temporal to the fovea locations were made on enhanced depth imaging optical coherence tomography (EDI-OCT) of the macula in all subjects using ImageJ software (National Institutes of Health, Bethesda, MD, USA). Results: SFCT in acute CSC was significantly larger than that in healthy eyes (P = 0.0001). SFCT in acute CSC did not differ significantly from that in chronic CSC eyes. Subfoveal LCVT and MCVT in acute CSC eyes were greater than those in healthy eyes (P = 0.02 and P = 0.03, respectively). Mean SFCT and MCVT in chronic CSC eyes were significantly larger than those in control eyes (P = 0.01 and P = 0.04, respectively). No significant difference in LCVT was observed between chronic and control eyes. Conclusion: Choroidal vasculature is altered in both acute and chronic CSC. SFCT, MCVT, and LCVT are higher in eyes with acute CSC. The thickening of medium choroidal vessels is still detectable in chronic CSC compared to control eyes.
AB - Purpose: To evaluate medium and large choroidal vessel layer thickness (MCVT and LCVT, respectively) in eyes with acute and chronic central serous chorioretinopathy (CSC) in comparison with age-matched controls. Methods: The study included 96 eyes of 96 patients with CSC, including 53 eyes with acute CSC, 43 eyes with chronic CSC, and 30 eyes of 30 age-matched normal subjects. Manual measurements of subfoveal choroidal thickness (SFCT), MCVT, and LCVT at subfoveal and 750 μm nasal and temporal to the fovea locations were made on enhanced depth imaging optical coherence tomography (EDI-OCT) of the macula in all subjects using ImageJ software (National Institutes of Health, Bethesda, MD, USA). Results: SFCT in acute CSC was significantly larger than that in healthy eyes (P = 0.0001). SFCT in acute CSC did not differ significantly from that in chronic CSC eyes. Subfoveal LCVT and MCVT in acute CSC eyes were greater than those in healthy eyes (P = 0.02 and P = 0.03, respectively). Mean SFCT and MCVT in chronic CSC eyes were significantly larger than those in control eyes (P = 0.01 and P = 0.04, respectively). No significant difference in LCVT was observed between chronic and control eyes. Conclusion: Choroidal vasculature is altered in both acute and chronic CSC. SFCT, MCVT, and LCVT are higher in eyes with acute CSC. The thickening of medium choroidal vessels is still detectable in chronic CSC compared to control eyes.
KW - Central Serous Chorioretinopathy
KW - Choroid
KW - Optical Coherence Tomography
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U2 - 10.4103/jovr.jovr_152_17
DO - 10.4103/jovr.jovr_152_17
M3 - Article
C2 - 31114653
AN - SCOPUS:85064923679
SN - 2008-2010
VL - 14
SP - 164
EP - 170
JO - Journal of Ophthalmic and Vision Research
JF - Journal of Ophthalmic and Vision Research
IS - 2
ER -