Evaluation of Children with Malignancies for Blood and Marrow Transplantation: A Report from the ASTCT Committee on Practice Guidelines

Ellen Fraint; Hisham Abdel-Azim; Neel S. Bhatt; Larisa Broglie; Asma Chattha; Mira Kohorst; Yiouli P. Ktena; Michelle A. Lee; Susie Long; Muna Qayed; Akshay Sharma; Heather Stefanski; Anant Vatsayan; Lisa Wray; Mehdi Hamadani; Paul A. Carpenter

doi:10.1016/j.jtct.2023.02.003

Evaluation of Children with Malignancies for Blood and Marrow Transplantation: A Report from the ASTCT Committee on Practice Guidelines

Ellen Fraint, Hisham Abdel-Azim, Neel S. Bhatt, Larisa Broglie, Asma Chattha, Mira Kohorst, Yiouli P. Ktena, Michelle A. Lee, Susie Long, Muna Qayed, Akshay Sharma, Heather Stefanski, Anant Vatsayan, Lisa Wray, Mehdi Hamadani, Paul A. Carpenter

School of Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Evaluation of a candidate for hematopoietic cell transplantation (HCT) is a complex process with substantial intercenter variability. Although literature providing guidance for evaluating the eligibility of adults is well established, similar guidance for children is lacking. To address gaps between adult recommendations and the specific needs of children, we convened a panel of pediatric HCT experts from a wide geographic range of American Society of Transplantation and Cellular Therapy (ASTCT) member institutions to offer recommendations for pediatric-focused pre-HCT evaluation. In this report from the ASTCT Committee on Practice Guidelines, we present a practical framework for evaluating children with malignancies who are candidates for HCT. We also highlight key differences from adults and emphasize areas of unmet need that require additional research to delineate best practices.

Original language	English (US)
Pages (from-to)	293-301
Number of pages	9
Journal	Transplantation and Cellular Therapy
Volume	29
Issue number	5
DOIs	https://doi.org/10.1016/j.jtct.2023.02.003
State	Published - May 2023

Keywords

Pediatric hematopoietic cell transplantation
Pediatric malignancy
Pretransplantation evaluation
Transplantation candidate

ASJC Scopus subject areas

Transplantation
Molecular Medicine
Hematology
Immunology and Allergy
Cell Biology

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10.1016/j.jtct.2023.02.003

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Fraint, E., Abdel-Azim, H., Bhatt, N. S., Broglie, L., Chattha, A., Kohorst, M., Ktena, Y. P., Lee, M. A., Long, S., Qayed, M., Sharma, A., Stefanski, H., Vatsayan, A., Wray, L., Hamadani, M., & Carpenter, P. A. (2023). Evaluation of Children with Malignancies for Blood and Marrow Transplantation: A Report from the ASTCT Committee on Practice Guidelines. Transplantation and Cellular Therapy, 29(5), 293-301. https://doi.org/10.1016/j.jtct.2023.02.003

Fraint, E, Abdel-Azim, H, Bhatt, NS, Broglie, L, Chattha, A, Kohorst, M, Ktena, YP, Lee, MA, Long, S, Qayed, M, Sharma, A, Stefanski, H, Vatsayan, A, Wray, L, Hamadani, M & Carpenter, PA 2023, 'Evaluation of Children with Malignancies for Blood and Marrow Transplantation: A Report from the ASTCT Committee on Practice Guidelines', Transplantation and Cellular Therapy, vol. 29, no. 5, pp. 293-301. https://doi.org/10.1016/j.jtct.2023.02.003

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abstract = "Evaluation of a candidate for hematopoietic cell transplantation (HCT) is a complex process with substantial intercenter variability. Although literature providing guidance for evaluating the eligibility of adults is well established, similar guidance for children is lacking. To address gaps between adult recommendations and the specific needs of children, we convened a panel of pediatric HCT experts from a wide geographic range of American Society of Transplantation and Cellular Therapy (ASTCT) member institutions to offer recommendations for pediatric-focused pre-HCT evaluation. In this report from the ASTCT Committee on Practice Guidelines, we present a practical framework for evaluating children with malignancies who are candidates for HCT. We also highlight key differences from adults and emphasize areas of unmet need that require additional research to delineate best practices.",

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author = "Ellen Fraint and Hisham Abdel-Azim and Bhatt, {Neel S.} and Larisa Broglie and Asma Chattha and Mira Kohorst and Ktena, {Yiouli P.} and Lee, {Michelle A.} and Susie Long and Muna Qayed and Akshay Sharma and Heather Stefanski and Anant Vatsayan and Lisa Wray and Mehdi Hamadani and Carpenter, {Paul A.}",

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doi = "10.1016/j.jtct.2023.02.003",

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AU - Kohorst, Mira

AU - Ktena, Yiouli P.

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AU - Long, Susie

AU - Qayed, Muna

AU - Sharma, Akshay

AU - Stefanski, Heather

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AU - Carpenter, Paul A.

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Evaluation of Children with Malignancies for Blood and Marrow Transplantation: A Report from the ASTCT Committee on Practice Guidelines

Abstract

Keywords

ASJC Scopus subject areas

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