TY - JOUR
T1 - EVALUATION OF A CLINICAL CASE-DEFINITION OF ACQUIRED IMMUNODEFICIENCY SYNDROME IN AFRICA
AU - Colebunders, Robert
AU - Francis, Henry
AU - Izaley, Lebughe
AU - Kabasele, Kanyinda
AU - Nzilambi, Nzila
AU - Van Der Groen, Guido
AU - Vercauteren, Gaby
AU - Mann, Jonathan M.
AU - Bila, Kapita
AU - Kakonde, Ndangi
AU - Ifoto, Limbaka
AU - Quinn, Thomas C.
AU - Curran, James W.
AU - Piot, Peter
PY - 1987/2/28
Y1 - 1987/2/28
N2 - A provisional clinical case-definition for acquired immunodeficiency syndrome (AIDS) developed by the World Health Organisation (WHO) for use in Africa was tested on 174 inpatients at Mama Yemo Hospital, Kinshasa, Zaire. In this hospital population with a 34% infection rate of human immunodeficiency virus (HIV), the clinical case-definition had a specificity of 90%, a sensitivity of 59%, and a predictive value of 74% for HIV seropositivity. These results support the use of the WHO clinical definition for AIDS in Africa. However, since HIV prevalence and disease expression vary, similar evaluations should be carried out in different regions.
AB - A provisional clinical case-definition for acquired immunodeficiency syndrome (AIDS) developed by the World Health Organisation (WHO) for use in Africa was tested on 174 inpatients at Mama Yemo Hospital, Kinshasa, Zaire. In this hospital population with a 34% infection rate of human immunodeficiency virus (HIV), the clinical case-definition had a specificity of 90%, a sensitivity of 59%, and a predictive value of 74% for HIV seropositivity. These results support the use of the WHO clinical definition for AIDS in Africa. However, since HIV prevalence and disease expression vary, similar evaluations should be carried out in different regions.
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U2 - 10.1016/S0140-6736(87)92099-X
DO - 10.1016/S0140-6736(87)92099-X
M3 - Article
C2 - 2881049
AN - SCOPUS:0023130091
SN - 0140-6736
VL - 329
SP - 492
EP - 494
JO - The Lancet
JF - The Lancet
IS - 8531
ER -