Evaluation and management of syphilis in the HIV-infected patient

Research output: Contribution to journalReview articlepeer-review

10 Scopus citations


Rates of syphilis continue to increase in the United States and HIV-infected patients make up a large proportion of cases. The interaction between syphilis and HIV is complex and still incompletely understood. Although diagnosis and management of HIV-infected patients with syphilis is, in general, similar to HIV-uninfected patients, the former may be at increased risk for complications. Recent data suggest that HIV-induced immunosuppression may alter the course of syphilis and that highly active antiretroviral therapy may have a beneficial effect on syphilis outcomes. Prevention strategies consisting of sexual risk assessments, condom use, treatment of infected partners, yearly screening for syphilis of all HIV-infected patients, and enhanced clinical and serologic follow-up of treated HIV-infected patients are critical components of a comprehensive approach to care.

Original languageEnglish (US)
Pages (from-to)140-146
Number of pages7
JournalCurrent Infectious Disease Reports
Issue number2
StatePublished - Mar 1 2010


  • Antiretroviral therapy
  • HIV
  • Neurosyphilis
  • Syphilis

ASJC Scopus subject areas

  • Infectious Diseases


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