Abstract
Three monkeys were provided concurrent access to water and ethanol in concentrations of either 8, 16 or 32% (w/v) during daily 3-hr sessions. The monkeys were those for whom ethanol had been established as a reinforcer in an earlier study in which only ethanol or water was available. Ethanol was preferred to water at all concentrations and volume of ethanol consumed was inversely related to ethanol concentration. Quantity of ethanol (g/kg of body wt.) consumed remained relatively constant, and blood ethanol determinations confirmed that the monkeys were drinking ethanol. Water drinking occured at negligible levels except by one monkey at 16 and 32% who followed ethanol drinking bouts by water bouts (chaser) in a manner similar to that reported in other studies. Two monkeys were also provided concurrent access to 8% ethanol and water during 23-hr daily sessions. Under these conditions, ethanol was consumed every few hours to the near exclusion of water. The significance of this study lies largely in its procedure; that is, the development and application of a concurrent water-ethanol preparation in which ethanol serves as a reinforcer for rhesus monkeys. This preparation should be useful in the evaluation of a wide range of factors suspected to control alcoholidrinking.
Original language | English (US) |
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Pages (from-to) | 777-782 |
Number of pages | 6 |
Journal | Pharmacology Biochemistry and Behavior |
Volume | 10 |
Issue number | 5 |
DOIs | |
State | Published - 1979 |
Externally published | Yes |
Keywords
- Concurrent schedule
- Ethanol
- Fixed-ratio
- Physical dependence
- Rhesus monkey
- Self-administration
ASJC Scopus subject areas
- Biochemistry
- Behavioral Neuroscience
- Pharmacology