@article{6caf03d2720748be8405455e58b3accb,
title = "Estimation of macular pigment optical density in the elderly: Test-retest variability and effect of optical blur in pseudophakic subjects",
abstract = "The reproducibility of macular pigment optical density (MPOD) estimates in the elderly was assessed in 40 subjects (age: 79.1 ± 3.5). Test-retest variability was good (Pearson's r coefficient: 0.734), with an average coefficient of variation (CV) of 18.4% and an intraclass correlation coefficient (ICC) of 0.96. The effect of optical blur on MPOD estimates was investigated in 22 elderly pseudophakic subjects (age: 79.9 ± 3.6) by comparing the baseline MPOD, obtained with an optimal correction, with MPODs obtained with a ±1.00-diopter optical blur. This optical blur did not cause differences in the MPOD estimates, its accuracy, or test duration.",
keywords = "Aging, Heterochromatic flicker photometry, Macular pigment optical density, Optical blur, Reliability",
author = "Gallaher, {Kevin T.} and Marco Mura and Todd, {Wm Andrew} and Harris, {Tarsha L.} and Emily Kenyon and Tamara Harris and Johnson, {Karen C.} and Suzanne Satterfield and Kritchevsky, {Stephen B.} and Alessandro Iannaccone",
note = "Funding Information: The authors gratefully acknowledge helpful comments and suggestions in the early stages of this study from Drs. Billy R. Wooten (Brown University, Providence, RI), B. Randy Hammond Jr. (Medical College of Georgia, Augusta, GA) and Julie A. Mares (University of Wisconsin, Madison, WI) and the helpful comments to this manuscript made by Dr. Ronald Shorr (UTHSC Dept. Preventive Medicine) and the Health ABC Publications Committee members; the assistance of the entire Health ABC staff at the Memphis study site; the technical assistance of Salwa M. Ahmed, Jeremy Racey, Deon Cistrunck, and Mary Lane; the assistance of Songmei Meng, Hongtao Zhai and Wentao Du with database creation and management; and the enthusiasm of all ARMA Study participants. Sources of Support: NEI grant K23 EY000409; NIA contracts N01 AG62101, N01 AG62103, N01 AG62106 and the Intramural NIA Research Program; International Retinal Research Foundation, Birmingham, AL and RPB, New York, NY (CDA to AI and unrestricted grant to the UTHSC Department of Ophthalmology). KG was the recipient of an intramural Medical Student Summer Research Fellowship, supported by training grant T35 DK07405 (UTHSC), and of an ARVO Foundation/Retina Research Foundation/Joseph M. and Eula C. Lawrence Travel Grant Award (ARVO 2005 meeting). TLH was the recipient of a Memphis McNair Program Summer Research Fellowship, supported by a grant from the US Department of Education P217A030229 to UTHSC. The MacularMetrics instrument utilized to measure macular pigment density in this study was purchased with the generous joint funding of Bausch & Lomb and Kemin Foods Corp.",
year = "2007",
month = apr,
doi = "10.1016/j.visres.2007.01.013",
language = "English (US)",
volume = "47",
pages = "1253--1259",
journal = "Vision Research",
issn = "0042-6989",
publisher = "Elsevier Limited",
number = "9",
}