Abstract
In this article we study the problem of estimating the parameters of a 2-D electrophysiological model of the heart from a set of temporal recordings of extracellular potentials. The chosen model is the reaction-diffusion model on the action potential proposed by Aliev and Panfilov. The strategy consists in building an error criterion based upon a comparison of depolarization times between the model and the measures. This error criterion is minimized in two steps: first a global and then a local adjustment of the model parameters. The feasibility of the approach is demonstrated on real measures on canine hearts, showing also the necessity to introduce anisotropy and probably a third spatial dimension in the model.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 256-266 |
| Number of pages | 11 |
| Journal | Lecture Notes in Computer Science |
| Volume | 3504 |
| DOIs | |
| State | Published - 2005 |
| Externally published | Yes |
| Event | Third International Workshop on Functional Imaging and Modeling of the Heart, FIMH 2005 - Barcelona, Spain Duration: Jun 2 2005 → Jun 4 2005 |
ASJC Scopus subject areas
- Theoretical Computer Science
- General Computer Science
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