TY - JOUR
T1 - Erratum
T2 - Hypoxia-inducible factor 2α (HIF-2α) heterozygous-null mice exhibit exaggerated carotid body sensitivity to hypoxia, breathing instability, and hypertension (Proceedings of the National Academy of Sciences of the United States of America (2011) 108 (3065-3070) DOI: 10.1073/pnas.1100064108)
AU - Peng, Ying Jie
AU - Nanduri, Jayasri
AU - Khan, Shakil A.
AU - Yuan, Guoxiang
AU - Wang, Ning
AU - Kinsman, Brian
AU - Vaddi, Damodara R.
AU - Kumar, Ganesh K.
AU - Garcia, Joseph A.
AU - Semenza, Gregg L.
AU - Prabhakar, Nanduri R.
N1 - Publisher Copyright:
© 2022 National Academy of Sciences. All rights reserved.
PY - 2022/9/20
Y1 - 2022/9/20
N2 - Correction for “Hypoxia-inducible factor 2α (HIF-2α) heterozygous-null mice exhibit exaggerated carotid body sensitivity to hypoxia, breathing instability, and hypertension,” by Ying-Jie Peng, Jayasri Nanduri, Shakil A. Khan, Guoxiang Yuan, Ning Wang, Brian Kinsman, Damodara R. Vaddi, Ganesh K. Kumar, Joseph A. Garcia, Gregg L. Semenza, and Nanduri R. Prabhakar, which was first published January 31, 2011; 10.1073/pnas.1100064108 (Proc. Natl. Acad. Sci. U.S.A. 108, 3065-3070). In response to an allegation of a splice in the HIF-2α panel of Fig. 3A, the authors note that: “We were unable to locate the original data shown in Figure 3A. However, we were able to locate an original blot of HIF-2α from a replicate experiment, which demonstrates reduced HIF-2α protein in adrenal medullae of 4 HIF-2α HET mice as compared to adrenal medullae of 3 wild type C57BL6 mice, on which HIF-2α HET mice were raised. Although there might have been splicing in the published blot, we regret not being able to confirm with the original blot. Nonetheless, the replicate blot demonstrated reduced HIF-2α expression in adrenal medullae in HIF-2α HET mice as originally reported in the published manuscript”. (Figure Presented).
AB - Correction for “Hypoxia-inducible factor 2α (HIF-2α) heterozygous-null mice exhibit exaggerated carotid body sensitivity to hypoxia, breathing instability, and hypertension,” by Ying-Jie Peng, Jayasri Nanduri, Shakil A. Khan, Guoxiang Yuan, Ning Wang, Brian Kinsman, Damodara R. Vaddi, Ganesh K. Kumar, Joseph A. Garcia, Gregg L. Semenza, and Nanduri R. Prabhakar, which was first published January 31, 2011; 10.1073/pnas.1100064108 (Proc. Natl. Acad. Sci. U.S.A. 108, 3065-3070). In response to an allegation of a splice in the HIF-2α panel of Fig. 3A, the authors note that: “We were unable to locate the original data shown in Figure 3A. However, we were able to locate an original blot of HIF-2α from a replicate experiment, which demonstrates reduced HIF-2α protein in adrenal medullae of 4 HIF-2α HET mice as compared to adrenal medullae of 3 wild type C57BL6 mice, on which HIF-2α HET mice were raised. Although there might have been splicing in the published blot, we regret not being able to confirm with the original blot. Nonetheless, the replicate blot demonstrated reduced HIF-2α expression in adrenal medullae in HIF-2α HET mice as originally reported in the published manuscript”. (Figure Presented).
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U2 - 10.1073/pnas.2210923119
DO - 10.1073/pnas.2210923119
M3 - Comment/debate
C2 - 36053741
AN - SCOPUS:85137170294
SN - 0027-8424
VL - 119
JO - Proceedings of the National Academy of Sciences of the United States of America
JF - Proceedings of the National Academy of Sciences of the United States of America
IS - 38
M1 - e2210923119
ER -