Epigenetic biomarkers of postpartum depression

Zachary Kaminsky, Jennifer L. Payne

Research output: Chapter in Book/Report/Conference proceedingChapter


Epigenetic changes in DNA methylation of genes alter gene transcription and are subject to environmental influences including exposure to hormones, stress, and other factors. This chapter describes epigenetic studies focused on postpartum depression. Two groups of studies are discussed including research examining a role for estrogen-influenced genes as well as research on epigenetic modification of the oxytocin receptor gene. Future work in this area should carefully define the phenotypes of participants including the presence or absence of preexisting mood disorders and the timing of onset of symptoms. Epigenetic studies of postpartum depression are an exciting area marrying the influence of biology (genetics) with the environment (hormone exposure).

Original languageEnglish (US)
Title of host publicationBiomarkers of Postpartum Psychiatric Disorders
Number of pages9
ISBN (Electronic)9780128155080
StatePublished - Jan 1 2019


  • Epigenetics
  • Estrogen
  • Hp1bp3
  • Oxytocin
  • Ttc9b

ASJC Scopus subject areas

  • General Psychology


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