Epidural tumors and metastases

Rory J. Petteys, Wesley Hsu, Carlos A. Bagley, Ziya L. Gokaslan

Research output: Chapter in Book/Report/Conference proceedingChapter


Cancer affects approximately 1.4 million Americans every year. Despite recent advancements and improvements in the care of these patents, approximately half will eventually succumb to their disease, a rate that has remained relatively unchanged over the last half century. In 2001, cancer ranked second to only heart disease in terms of mortality in the USA, accounting for approximately 23% of all deaths. The most common causes of death in oncology patients are complications related to metastasis of their primary disease [52]. The skeletal system is the third most common site for metastases, behind the lung and liver. Within the skeletal system, the spinal column is the most commonly affected site [6]. In fact, metastases are the most common type of neoplastic lesion found in the spinal column, comprising up to 90% of all spinal tumors in some series. Autopsy studies also demonstrate that upwards of 90% of cancer patients will have spinal metastatic deposits at the time of death. Of those with spinal metastases, up to 50% will require some form of treatment for their spinal metastasis and 5-10% will require surgery [3, 5, 47, 52].

Original languageEnglish (US)
Title of host publicationOncology of CNS Tumors
PublisherSpringer Berlin Heidelberg
Number of pages19
ISBN (Print)9783642028731
StatePublished - Dec 1 2010

ASJC Scopus subject areas

  • Medicine(all)


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