Epidemiology of Hepatocellular Carcinoma

Kelly J. Lafaro; Aram N. Demirjian; Timothy M. Pawlik

doi:10.1016/j.soc.2014.09.001

Epidemiology of Hepatocellular Carcinoma

Kelly J. Lafaro, Aram N. Demirjian, Timothy M. Pawlik

Research output: Contribution to journal › Review article › peer-review

197 Scopus citations

Abstract

Hepatocellular carcinoma (HCC) is the most common histologic type of primary liver cancer, accounting for between 85% and 90% of these malignancies. The overall prognosis of patients with liver cancer is poor, and an understanding of this disease and its risk factors is crucial for screening at-risk individuals, early recognition, and timely diagnosis. Most HCCs arise in the background of chronic liver disease caused by hepatitis B virus, hepatitis C virus, and chronic excessive alcohol intake. These underlying causes are characterized by marked variations in geography, gender, and other well-documented risk factors, some of which are potentially preventable.

Original language	English (US)
Pages (from-to)	1-17
Number of pages	17
Journal	Surgical Oncology Clinics of North America
Volume	24
Issue number	1
DOIs	https://doi.org/10.1016/j.soc.2014.09.001
State	Published - Jan 1 2015

Keywords

Aflatoxin
Chronic liver disease
Cirrhosis
Hepatitis b
Hepatitis c
Hepatocellular carcinoma
Incidence
Risk factors

ASJC Scopus subject areas

Surgery
Oncology

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10.1016/j.soc.2014.09.001

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title = "Epidemiology of Hepatocellular Carcinoma",

abstract = "Hepatocellular carcinoma (HCC) is the most common histologic type of primary liver cancer, accounting for between 85% and 90% of these malignancies. The overall prognosis of patients with liver cancer is poor, and an understanding of this disease and its risk factors is crucial for screening at-risk individuals, early recognition, and timely diagnosis. Most HCCs arise in the background of chronic liver disease caused by hepatitis B virus, hepatitis C virus, and chronic excessive alcohol intake. These underlying causes are characterized by marked variations in geography, gender, and other well-documented risk factors, some of which are potentially preventable.",

keywords = "Aflatoxin, Chronic liver disease, Cirrhosis, Hepatitis b, Hepatitis c, Hepatocellular carcinoma, Incidence, Risk factors",

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T1 - Epidemiology of Hepatocellular Carcinoma

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AU - Demirjian, Aram N.

AU - Pawlik, Timothy M.

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N2 - Hepatocellular carcinoma (HCC) is the most common histologic type of primary liver cancer, accounting for between 85% and 90% of these malignancies. The overall prognosis of patients with liver cancer is poor, and an understanding of this disease and its risk factors is crucial for screening at-risk individuals, early recognition, and timely diagnosis. Most HCCs arise in the background of chronic liver disease caused by hepatitis B virus, hepatitis C virus, and chronic excessive alcohol intake. These underlying causes are characterized by marked variations in geography, gender, and other well-documented risk factors, some of which are potentially preventable.

AB - Hepatocellular carcinoma (HCC) is the most common histologic type of primary liver cancer, accounting for between 85% and 90% of these malignancies. The overall prognosis of patients with liver cancer is poor, and an understanding of this disease and its risk factors is crucial for screening at-risk individuals, early recognition, and timely diagnosis. Most HCCs arise in the background of chronic liver disease caused by hepatitis B virus, hepatitis C virus, and chronic excessive alcohol intake. These underlying causes are characterized by marked variations in geography, gender, and other well-documented risk factors, some of which are potentially preventable.

KW - Aflatoxin

KW - Chronic liver disease

KW - Cirrhosis

KW - Hepatitis b

KW - Hepatitis c

KW - Hepatocellular carcinoma

KW - Incidence

KW - Risk factors

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Epidemiology of Hepatocellular Carcinoma

Abstract

Keywords

ASJC Scopus subject areas

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