Epidemiology of Hepatocellular Carcinoma

Kelly J. Lafaro, Aram N. Demirjian, Timothy M. Pawlik

Research output: Contribution to journalReview articlepeer-review

197 Scopus citations


Hepatocellular carcinoma (HCC) is the most common histologic type of primary liver cancer, accounting for between 85% and 90% of these malignancies. The overall prognosis of patients with liver cancer is poor, and an understanding of this disease and its risk factors is crucial for screening at-risk individuals, early recognition, and timely diagnosis. Most HCCs arise in the background of chronic liver disease caused by hepatitis B virus, hepatitis C virus, and chronic excessive alcohol intake. These underlying causes are characterized by marked variations in geography, gender, and other well-documented risk factors, some of which are potentially preventable.

Original languageEnglish (US)
Pages (from-to)1-17
Number of pages17
JournalSurgical Oncology Clinics of North America
Issue number1
StatePublished - Jan 1 2015


  • Aflatoxin
  • Chronic liver disease
  • Cirrhosis
  • Hepatitis b
  • Hepatitis c
  • Hepatocellular carcinoma
  • Incidence
  • Risk factors

ASJC Scopus subject areas

  • Surgery
  • Oncology


Dive into the research topics of 'Epidemiology of Hepatocellular Carcinoma'. Together they form a unique fingerprint.

Cite this