Epidemiology of hepatitis E virus infection in Turkey

D. L. Thomas, T. C. Quinn, R. W. Mahley, K. E. Palaoglu, S. Badur

Research output: Contribution to journalArticlepeer-review

78 Scopus citations


The seroprevalence and risk factors for infection with hepatitis E virus (HEV) were analysed in five regions of Turkey, where one-third of acute hepatitis cases are non-A, non-B. Antibodies to HEV (anti-HEV) were found in 80 (5·9%) of 1350 subjects. Independent predictors of anti-HEV were age over 25 years, less than elementary education, antibodies to hepatitis C virus, and residence in the warmest region (Adana). Whereas none of 105 subjects in the second decade of life were HEV seropositive, 17 (3·7%) of 464 and 28 (9·1 %) of 308 of those in the third and fourth decades of life, respectively, had anti-HEV (p<0·001). These data demonstrate that in Turkey HEV is more prevalent in warmer regions and in adults, beginning in the third decade of life.

Original languageEnglish (US)
Pages (from-to)1561-1562
Number of pages2
JournalThe Lancet
Issue number8860
StatePublished - Jun 19 1993

ASJC Scopus subject areas

  • Medicine(all)


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