Abstract
Hymenoptera venom allergy is a typical IgE-mediated reaction caused by sensitization to 1 or more allergens of the venom, and accounts for 1.5% to 34% of all cases of anaphylaxis. Patients suffering from mastocytosis are more susceptible to the anaphylactic reactions to an insect sting. This article aims to answer the most important clinical questions raised by the diagnosis and treatment of insect venom allergy in mastocytosis patients. Total avoidance of Hymenoptera is not feasible, and there is no preventive pharmacologic treatment available, although venom immunotherapy reduces the risk of subsequent systemic reactions.
Original language | English (US) |
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Pages (from-to) | 365-381 |
Number of pages | 17 |
Journal | Immunology and Allergy Clinics of North America |
Volume | 34 |
Issue number | 2 |
DOIs | |
State | Published - May 2014 |
Keywords
- Hymenoptera venom allergy
- Immunoglobulin E serology
- Mastocytosis
- Venom immunotherapy
ASJC Scopus subject areas
- Immunology and Allergy
- Immunology