Epidemiologic clues to the causes and routes to prevention of Alzheimer disease

Johns C.S. Breitner

Research output: Contribution to journalReview articlepeer-review

8 Scopus citations


Identification of epidemiologic risk factors serves many purposes. These include 1) identification of high risk groups as potential targets for interventions; 2) identification of the candidate interventions (when the risk factor is susceptible to modification); and 3) suggestion of previously unsuspected causal mechanisms (when the risk relationship is unexpected and not readily explained by current causal theories). Two possible risk relationships will be discussed - one now well known and the other novel - that may provide a means of reducing the risk of Alzheimer's disease (AD). I will also suggest a causal theory that encompasses these epidemiologic observations and other recent data.

Original languageEnglish (US)
Pages (from-to)251-254
Number of pages4
JournalJournal of Neural Transmission, Supplement
Issue number59
StatePublished - 2000

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology
  • Psychiatry and Mental health
  • Biological Psychiatry


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