Epibulbar IGA Plasmacytoma Occurring in Multiple Myeloma

Rudolph M. Franklin; Kenneth R. Kenyon; W. Richard Green; Rein Saral; Richard Humphrey

doi:10.1001/archopht.1982.01030030453015

Epibulbar IGA Plasmacytoma Occurring in Multiple Myeloma

Rudolph M. Franklin
, Kenneth R. Kenyon
, W. Richard Green
, Rein Saral
, Richard Humphrey

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

The ophthalmic manifestations of a 51-year-old man with multiple myeloma included exudative retinal detachments and multiple epibulbar plasmacytomas. The retinal changes resolved with treatment for systemic effects, and the IgAproducing plasmacytomas rapidly resolved with local irradiation. The young age of onset (37 years), the prolonged course (14 years), and the IgA M protein and epibulbar involvement were, collectively, unusual findings in multiple myeloma. The presence of epibulbar, gastrointestinal tract, and prostate involvement suggested a homing mechanism of IgAcommitted cells to mucosal surfaces.

Original language	English (US)
Pages (from-to)	451-456
Number of pages	6
Journal	Archives of Ophthalmology
Volume	100
Issue number	3
DOIs	https://doi.org/10.1001/archopht.1982.01030030453015
State	Published - Mar 1982
Externally published	Yes

ASJC Scopus subject areas

Ophthalmology

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10.1001/archopht.1982.01030030453015

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title = "Epibulbar IGA Plasmacytoma Occurring in Multiple Myeloma",

abstract = "The ophthalmic manifestations of a 51-year-old man with multiple myeloma included exudative retinal detachments and multiple epibulbar plasmacytomas. The retinal changes resolved with treatment for systemic effects, and the IgAproducing plasmacytomas rapidly resolved with local irradiation. The young age of onset (37 years), the prolonged course (14 years), and the IgA M protein and epibulbar involvement were, collectively, unusual findings in multiple myeloma. The presence of epibulbar, gastrointestinal tract, and prostate involvement suggested a homing mechanism of IgAcommitted cells to mucosal surfaces.",

author = "Franklin, \{Rudolph M.\} and Kenyon, \{Kenneth R.\} and Green, \{W. Richard\} and Rein Saral and Richard Humphrey",

year = "1982",

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doi = "10.1001/archopht.1982.01030030453015",

language = "English (US)",

volume = "100",

pages = "451--456",

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T1 - Epibulbar IGA Plasmacytoma Occurring in Multiple Myeloma

AU - Franklin, Rudolph M.

AU - Kenyon, Kenneth R.

AU - Green, W. Richard

AU - Saral, Rein

AU - Humphrey, Richard

PY - 1982/3

Y1 - 1982/3

N2 - The ophthalmic manifestations of a 51-year-old man with multiple myeloma included exudative retinal detachments and multiple epibulbar plasmacytomas. The retinal changes resolved with treatment for systemic effects, and the IgAproducing plasmacytomas rapidly resolved with local irradiation. The young age of onset (37 years), the prolonged course (14 years), and the IgA M protein and epibulbar involvement were, collectively, unusual findings in multiple myeloma. The presence of epibulbar, gastrointestinal tract, and prostate involvement suggested a homing mechanism of IgAcommitted cells to mucosal surfaces.

AB - The ophthalmic manifestations of a 51-year-old man with multiple myeloma included exudative retinal detachments and multiple epibulbar plasmacytomas. The retinal changes resolved with treatment for systemic effects, and the IgAproducing plasmacytomas rapidly resolved with local irradiation. The young age of onset (37 years), the prolonged course (14 years), and the IgA M protein and epibulbar involvement were, collectively, unusual findings in multiple myeloma. The presence of epibulbar, gastrointestinal tract, and prostate involvement suggested a homing mechanism of IgAcommitted cells to mucosal surfaces.

UR - https://www.scopus.com/pages/publications/0020041854

UR - https://www.scopus.com/pages/publications/0020041854#tab=citedBy

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JO - Archives of Ophthalmology

JF - Archives of Ophthalmology

IS - 3

ER -

Epibulbar IGA Plasmacytoma Occurring in Multiple Myeloma

Abstract

ASJC Scopus subject areas

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