Epibulbar IGA Plasmacytoma Occurring in Multiple Myeloma

Rudolph M. Franklin, Kenneth R. Kenyon, W. Richard Green, Rein Saral, Richard Humphrey

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


The ophthalmic manifestations of a 51-year-old man with multiple myeloma included exudative retinal detachments and multiple epibulbar plasmacytomas. The retinal changes resolved with treatment for systemic effects, and the IgAproducing plasmacytomas rapidly resolved with local irradiation. The young age of onset (37 years), the prolonged course (14 years), and the IgA M protein and epibulbar involvement were, collectively, unusual findings in multiple myeloma. The presence of epibulbar, gastrointestinal tract, and prostate involvement suggested a homing mechanism of IgAcommitted cells to mucosal surfaces.

Original languageEnglish (US)
Pages (from-to)451-456
Number of pages6
JournalArchives of ophthalmology
Issue number3
StatePublished - Mar 1982
Externally publishedYes

ASJC Scopus subject areas

  • Ophthalmology


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