TY - JOUR
T1 - Epi-LASIK
T2 - A confocal microscopy analysis of the corneal epithelium and anterior stroma
AU - Ramírez, Manuel
AU - Hernández-Quintela, Everardo
AU - Naranjo-Tackman, Ramón
PY - 2012/7
Y1 - 2012/7
N2 - ■ BACKGROUND AND OBJECTIVE: To evaluate the confocal microscopy findings at the corneal epithelium and anterior stroma after epi-LASIK. ■ PATIENTS AND METHODS: Twelve eyes of 12 patients underwent epi-LASIK. A central scan of the total corneal thickness was taken with the confocal microscope before and at 2 weeks and 1 month after surgery. Corneal epithelial thickness was measured and the anterior stroma morphology was also analyzed. ■ RESULTS: Mean epithelial thickness was 46.5 ±5.5 μm before surgery. It had decreased by 23.4% (35.6 ± 5.6 μm) at 2 weeks and by 22.1% (36.2 ± 5 μm) at 1 month postoperatively, compared with the preoperative measurement. The change in thickness was statistically significant. The anterior stroma showed keratocyte activation at 2 weeks and 1 month after surgery. ■ CONCLUSION: Corneal epithelial thickness was decreased up to 1 month after surgery. The stromal ablation zone showed keratocyte activation in both postoperative measurements.
AB - ■ BACKGROUND AND OBJECTIVE: To evaluate the confocal microscopy findings at the corneal epithelium and anterior stroma after epi-LASIK. ■ PATIENTS AND METHODS: Twelve eyes of 12 patients underwent epi-LASIK. A central scan of the total corneal thickness was taken with the confocal microscope before and at 2 weeks and 1 month after surgery. Corneal epithelial thickness was measured and the anterior stroma morphology was also analyzed. ■ RESULTS: Mean epithelial thickness was 46.5 ±5.5 μm before surgery. It had decreased by 23.4% (35.6 ± 5.6 μm) at 2 weeks and by 22.1% (36.2 ± 5 μm) at 1 month postoperatively, compared with the preoperative measurement. The change in thickness was statistically significant. The anterior stroma showed keratocyte activation at 2 weeks and 1 month after surgery. ■ CONCLUSION: Corneal epithelial thickness was decreased up to 1 month after surgery. The stromal ablation zone showed keratocyte activation in both postoperative measurements.
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U2 - 10.3928/15428877-20120618-03
DO - 10.3928/15428877-20120618-03
M3 - Article
C2 - 22788583
AN - SCOPUS:84866762160
SN - 1542-8877
VL - 43
SP - 319
EP - 322
JO - Ophthalmic Surgery Lasers and Imaging
JF - Ophthalmic Surgery Lasers and Imaging
IS - 4
ER -