Environmental risk factors for alzheimer's disease: Their relationship to age of onset and to familial or sporadic types

A. S. Henderson, A. F. Jorm, A. E. Korten, H. Creasey, E. McCusker, G. A. Broe, W. Longley, J. C. Anthony

Research output: Contribution to journalArticlepeer-review

Abstract

Data from a case-control study of Alzheimer's disease (AD) were analysed in relation to age of onset and familial/sporadic status. The analyses were restricted to environmental exposures which might injure the brain. Later-onset AD was found to be positively associated with starvation/malnutrition and with nose-picking and negatively with analgesics, while earlier-onset was associated with physical underactivity and nervous breakdown more than 10 years before. Sporadic AD was associated with starvation/malnutrition and with head injury. These analyses merit replication in other large case-control studies of AD.

Original languageEnglish (US)
Pages (from-to)429-436
Number of pages8
JournalPsychological medicine
Volume22
Issue number2
DOIs
StatePublished - May 1992

ASJC Scopus subject areas

  • Applied Psychology
  • Psychiatry and Mental health

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