Enhancement of cardiac allografts in rats at the major AbG locus. I. Synergistic effect of specific and non-specific immunosuppression

W. Rowinski; S. Stepkowski; T. Ryffa; B. Wasowska

Enhancement of cardiac allografts in rats at the major AbG locus. I. Synergistic effect of specific and non-specific immunosuppression

W. Rowinski, S. Stepkowski, T. Ryffa, B. Wasowska

Research output: Contribution to journal › Article › peer-review

Abstract

Investigations of the specific and nonspecific immunosuppression of heart transplants in rats are presentd. Pretreatment of the Wistar recipient of the August heart with donor strain cellular antigen and anti-donor hyperimmune serum 11 and 10 days before transplantation caused enhancement of the heart graft in this strain combination differing in the major AgB histocompatibility locus. Combination of that protocol with non-specific immunosuppression, i.e. ATS treatment caused synergistic effect. Heart grafts in animal treated with that full protocol of biological immunosuppression survived for 50.8 days.

Original language	English (US)
Pages (from-to)	1009-1012
Number of pages	4
Journal	Archivum Immunologiae et Therapiae Experimentalis
Volume	26
Issue number	1-6
State	Published - 1979
Externally published	Yes

ASJC Scopus subject areas

Immunology

Cite this

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title = "Enhancement of cardiac allografts in rats at the major AbG locus. I. Synergistic effect of specific and non-specific immunosuppression",

abstract = "Investigations of the specific and nonspecific immunosuppression of heart transplants in rats are presentd. Pretreatment of the Wistar recipient of the August heart with donor strain cellular antigen and anti-donor hyperimmune serum 11 and 10 days before transplantation caused enhancement of the heart graft in this strain combination differing in the major AgB histocompatibility locus. Combination of that protocol with non-specific immunosuppression, i.e. ATS treatment caused synergistic effect. Heart grafts in animal treated with that full protocol of biological immunosuppression survived for 50.8 days.",

author = "W. Rowinski and S. Stepkowski and T. Ryffa and B. Wasowska",

year = "1979",

language = "English (US)",

volume = "26",

pages = "1009--1012",

journal = "Archivum Immunologiae et Therapiae Experimentalis",

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AU - Rowinski, W.

AU - Stepkowski, S.

AU - Ryffa, T.

AU - Wasowska, B.

PY - 1979

Y1 - 1979

N2 - Investigations of the specific and nonspecific immunosuppression of heart transplants in rats are presentd. Pretreatment of the Wistar recipient of the August heart with donor strain cellular antigen and anti-donor hyperimmune serum 11 and 10 days before transplantation caused enhancement of the heart graft in this strain combination differing in the major AgB histocompatibility locus. Combination of that protocol with non-specific immunosuppression, i.e. ATS treatment caused synergistic effect. Heart grafts in animal treated with that full protocol of biological immunosuppression survived for 50.8 days.

AB - Investigations of the specific and nonspecific immunosuppression of heart transplants in rats are presentd. Pretreatment of the Wistar recipient of the August heart with donor strain cellular antigen and anti-donor hyperimmune serum 11 and 10 days before transplantation caused enhancement of the heart graft in this strain combination differing in the major AgB histocompatibility locus. Combination of that protocol with non-specific immunosuppression, i.e. ATS treatment caused synergistic effect. Heart grafts in animal treated with that full protocol of biological immunosuppression survived for 50.8 days.

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JO - Archivum Immunologiae et Therapiae Experimentalis

JF - Archivum Immunologiae et Therapiae Experimentalis

IS - 1-6

ER -

Enhancement of cardiac allografts in rats at the major AbG locus. I. Synergistic effect of specific and non-specific immunosuppression

Abstract

ASJC Scopus subject areas

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