Endothelial progenitor cells

Aarif Y. Khakoo, Toren Finkel

Research output: Contribution to journalArticlepeer-review

306 Scopus citations


Endothelial progenitor cells are a circulating, bone marrow-derived cell population that appears to participate in both vasculogenesis and vascular homeostasis. Questions persist regarding their functional characteristics, as well as the precise panel of cell surface markers that uniquely define this newly described progenitor cell population. We review experimental results obtained from both animal studies and recent clinical trials that suggest this cell type may have tremendous therapeutic potential for a wide range of human diseases.

Original languageEnglish (US)
Pages (from-to)79-101
Number of pages23
JournalAnnual Review of Medicine
StatePublished - 2005
Externally publishedYes


  • Angiogenesis
  • Cell therapy
  • Stem cells
  • Vascular biology
  • Vasculogenesis

ASJC Scopus subject areas

  • Cell Biology
  • General Medicine


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