Endothelial progenitor cells

Aarif Y. Khakoo; Toren Finkel

doi:10.1146/annurev.med.56.090203.104149

Endothelial progenitor cells

Aarif Y. Khakoo, Toren Finkel

Research output: Contribution to journal › Article › peer-review

306 Scopus citations

Abstract

Endothelial progenitor cells are a circulating, bone marrow-derived cell population that appears to participate in both vasculogenesis and vascular homeostasis. Questions persist regarding their functional characteristics, as well as the precise panel of cell surface markers that uniquely define this newly described progenitor cell population. We review experimental results obtained from both animal studies and recent clinical trials that suggest this cell type may have tremendous therapeutic potential for a wide range of human diseases.

Original language	English (US)
Pages (from-to)	79-101
Number of pages	23
Journal	Annual Review of Medicine
Volume	56
DOIs	https://doi.org/10.1146/annurev.med.56.090203.104149
State	Published - 2005
Externally published	Yes

Keywords

Angiogenesis
Cell therapy
Stem cells
Vascular biology
Vasculogenesis

ASJC Scopus subject areas

Cell Biology
General Medicine

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10.1146/annurev.med.56.090203.104149

Cite this

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title = "Endothelial progenitor cells",

abstract = "Endothelial progenitor cells are a circulating, bone marrow-derived cell population that appears to participate in both vasculogenesis and vascular homeostasis. Questions persist regarding their functional characteristics, as well as the precise panel of cell surface markers that uniquely define this newly described progenitor cell population. We review experimental results obtained from both animal studies and recent clinical trials that suggest this cell type may have tremendous therapeutic potential for a wide range of human diseases.",

keywords = "Angiogenesis, Cell therapy, Stem cells, Vascular biology, Vasculogenesis",

author = "Khakoo, {Aarif Y.} and Toren Finkel",

year = "2005",

doi = "10.1146/annurev.med.56.090203.104149",

language = "English (US)",

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AU - Khakoo, Aarif Y.

AU - Finkel, Toren

PY - 2005

Y1 - 2005

N2 - Endothelial progenitor cells are a circulating, bone marrow-derived cell population that appears to participate in both vasculogenesis and vascular homeostasis. Questions persist regarding their functional characteristics, as well as the precise panel of cell surface markers that uniquely define this newly described progenitor cell population. We review experimental results obtained from both animal studies and recent clinical trials that suggest this cell type may have tremendous therapeutic potential for a wide range of human diseases.

AB - Endothelial progenitor cells are a circulating, bone marrow-derived cell population that appears to participate in both vasculogenesis and vascular homeostasis. Questions persist regarding their functional characteristics, as well as the precise panel of cell surface markers that uniquely define this newly described progenitor cell population. We review experimental results obtained from both animal studies and recent clinical trials that suggest this cell type may have tremendous therapeutic potential for a wide range of human diseases.

KW - Angiogenesis

KW - Cell therapy

KW - Stem cells

KW - Vascular biology

KW - Vasculogenesis

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DO - 10.1146/annurev.med.56.090203.104149

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AN - SCOPUS:14544282964

SN - 0066-4219

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EP - 101

JO - Annual Review of Medicine

JF - Annual Review of Medicine

ER -

Endothelial progenitor cells

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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