Endoscopic forward-viewing optical coherence tomography and angiography with MHz swept source

Kaicheng Liang; Osman O. Ahsen; Zhao Wang; Hsiang Chieh Lee; Wenxuan Liang; Benjamin M. Potsaid; Tsung Han Tsai; Michael G. Giacomelli; Vijaysekhar Jayaraman; Hiroshi Mashimo; Xingde Li; James G. Fujimoto

doi:10.1364/OL.42.003193

Endoscopic forward-viewing optical coherence tomography and angiography with MHz swept source

Kaicheng Liang, Osman O. Ahsen, Zhao Wang, Hsiang Chieh Lee, Wenxuan Liang, Benjamin M. Potsaid, Tsung Han Tsai, Michael G. Giacomelli, Vijaysekhar Jayaraman, Hiroshi Mashimo, Xingde Li, James G. Fujimoto

School of Medicine

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

Endoscopic optical coherence tomography (OCT) instruments are mostly side viewing and rely on at least one proximal scan, thus limiting accuracy of volumetric imaging and en face visualization. Previous forward-viewing OCT devices had limited axial scan speeds. We report a forward-viewing fiber scanning 3D-OCT probe with 900 μm field of view and 5 μm transverse resolution, imaging at 1 MHz axial scan rate in the human gastrointestinal tract. The probe is 3.3 mm diameter and 20 mm rigid length, thus enabling passage through the endoscopic channel. The scanner has 1.8 kHz resonant frequency, and each volumetric acquisition takes 0.17 s with 2 volumes∕s display. 3D-OCT and angiography imaging of the colon was performed during surveillance colonoscopy.

Original language	English (US)
Pages (from-to)	3193-3196
Number of pages	4
Journal	Optics Letters
Volume	42
Issue number	16
DOIs	https://doi.org/10.1364/OL.42.003193
State	Published - Aug 15 2017

ASJC Scopus subject areas

Atomic and Molecular Physics, and Optics

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10.1364/OL.42.003193

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title = "Endoscopic forward-viewing optical coherence tomography and angiography with MHz swept source",

abstract = "Endoscopic optical coherence tomography (OCT) instruments are mostly side viewing and rely on at least one proximal scan, thus limiting accuracy of volumetric imaging and en face visualization. Previous forward-viewing OCT devices had limited axial scan speeds. We report a forward-viewing fiber scanning 3D-OCT probe with 900 μm field of view and 5 μm transverse resolution, imaging at 1 MHz axial scan rate in the human gastrointestinal tract. The probe is 3.3 mm diameter and 20 mm rigid length, thus enabling passage through the endoscopic channel. The scanner has 1.8 kHz resonant frequency, and each volumetric acquisition takes 0.17 s with 2 volumes∕s display. 3D-OCT and angiography imaging of the colon was performed during surveillance colonoscopy.",

author = "Kaicheng Liang and Ahsen, {Osman O.} and Zhao Wang and Lee, {Hsiang Chieh} and Wenxuan Liang and Potsaid, {Benjamin M.} and Tsai, {Tsung Han} and Giacomelli, {Michael G.} and Vijaysekhar Jayaraman and Hiroshi Mashimo and Xingde Li and Fujimoto, {James G.}",

note = "Funding Information: National Institutes of Health (NIH) (F32-CA183400, R01-CA075289, R01-CA178636, R01-EY011289, R44-CA101067); Air Force Office of Scientific Research (AFOSR) (FA9550-12-1-0499, FA9550-15-1-0473). KCL acknowledges an Agency for Science, Technology and Research (Singapore) graduate fellowship. Publisher Copyright: {\textcopyright} 2017 Optical Society of America.",

year = "2017",

month = aug,

day = "15",

doi = "10.1364/OL.42.003193",

language = "English (US)",

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pages = "3193--3196",

journal = "Optics Letters",

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T1 - Endoscopic forward-viewing optical coherence tomography and angiography with MHz swept source

AU - Liang, Kaicheng

AU - Ahsen, Osman O.

AU - Wang, Zhao

AU - Lee, Hsiang Chieh

AU - Liang, Wenxuan

AU - Potsaid, Benjamin M.

AU - Tsai, Tsung Han

AU - Giacomelli, Michael G.

AU - Jayaraman, Vijaysekhar

AU - Mashimo, Hiroshi

AU - Li, Xingde

AU - Fujimoto, James G.

N1 - Funding Information: National Institutes of Health (NIH) (F32-CA183400, R01-CA075289, R01-CA178636, R01-EY011289, R44-CA101067); Air Force Office of Scientific Research (AFOSR) (FA9550-12-1-0499, FA9550-15-1-0473). KCL acknowledges an Agency for Science, Technology and Research (Singapore) graduate fellowship. Publisher Copyright: © 2017 Optical Society of America.

PY - 2017/8/15

Y1 - 2017/8/15

N2 - Endoscopic optical coherence tomography (OCT) instruments are mostly side viewing and rely on at least one proximal scan, thus limiting accuracy of volumetric imaging and en face visualization. Previous forward-viewing OCT devices had limited axial scan speeds. We report a forward-viewing fiber scanning 3D-OCT probe with 900 μm field of view and 5 μm transverse resolution, imaging at 1 MHz axial scan rate in the human gastrointestinal tract. The probe is 3.3 mm diameter and 20 mm rigid length, thus enabling passage through the endoscopic channel. The scanner has 1.8 kHz resonant frequency, and each volumetric acquisition takes 0.17 s with 2 volumes∕s display. 3D-OCT and angiography imaging of the colon was performed during surveillance colonoscopy.

AB - Endoscopic optical coherence tomography (OCT) instruments are mostly side viewing and rely on at least one proximal scan, thus limiting accuracy of volumetric imaging and en face visualization. Previous forward-viewing OCT devices had limited axial scan speeds. We report a forward-viewing fiber scanning 3D-OCT probe with 900 μm field of view and 5 μm transverse resolution, imaging at 1 MHz axial scan rate in the human gastrointestinal tract. The probe is 3.3 mm diameter and 20 mm rigid length, thus enabling passage through the endoscopic channel. The scanner has 1.8 kHz resonant frequency, and each volumetric acquisition takes 0.17 s with 2 volumes∕s display. 3D-OCT and angiography imaging of the colon was performed during surveillance colonoscopy.

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Endoscopic forward-viewing optical coherence tomography and angiography with MHz swept source

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