Endocrinologic management of hyperthyroidism and the impact on thyroid eye disease

Fatemeh Rajaii, Shivani Gupta, Raymond S. Douglas

Research output: Contribution to journalReview articlepeer-review


Thyroid eye disease (TED) is a complex inflammatory disease with a poorly understood etiopathogenesis. It is often, but not always, associated with Graves' disease and the endocrinologic manifestations of hyperthyroidism. Controversy exists regarding optimal treatment of hyperthyroidism especially with regard to the progression of orbitopathy. We review the literature examining the effectiveness of antithyroid drugs, radioactive iodine, and thyroidectomy for long-term endocrinologic management, and their effect on the progression of TED. In formulating an individualized treatment plan, considerations include rates of recurrent hyperthyroidism, treatment-associated complications, and effect on TED progression.

Original languageEnglish (US)
Pages (from-to)69-72
Number of pages4
JournalTaiwan Journal of Ophthalmology
Issue number2
StatePublished - Jun 2014
Externally publishedYes


  • Antithyroid drugs
  • Graves' disease
  • Hyperthyroidism
  • Radioactive iodine
  • Thyroidectomy

ASJC Scopus subject areas

  • Ophthalmology


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