Endocrine assays in the monitoring of pregnancy. Clinical identification of high-risk pregnancies

R. C. Rock, D. W. Chan, M. T. Perlstein

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations

Abstract

Application of hormone assays to the monitoring of high-risk pregnancies is most helpful if the assays are performed serially in any one patient to offset marked intraindividual and interindividual biological variability. The problem of clinically defining and identifying abnormal fetal conditions, such as intrauterine growth retardation, makes the correlation between clinical outcomes and laboratory tests difficult. As a result, most hormone tests do not yield optimal sensitivity and specificity. These assays have thus been adjuncts to other diagnostic procedures in clinical decision-making.

Original languageEnglish (US)
Pages (from-to)157-179
Number of pages23
JournalClinics in laboratory medicine
Volume1
Issue number2
DOIs
StatePublished - 1981

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Biochemistry, medical

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