En bloc spondylectomy for treatment of tumor-induced osteomalacia: Case report

Daniel M. Sciubba, Rory J. Petteys, Sophia F. Shakur, Ziya L. Gokaslan, Edward F. McCarthy, Michael T. Collins, Matthew J. McGirt, Patrick C. Hsieh, Clarke S. Nelson, Jean Paul Wolinsky

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20 Scopus citations


En bloc spondylectomy represents a radical resection of a spinal segment most often reserved for patients presenting with a primary extradural spine tumor or a solitary metastasis in the setting of an indolent, well-controlled systemic malignancy. The authors report a case in which en bloc spondylectomy was conducted to control a metabolically active spine tumor. A 56-year-old woman, who suffered from severe tumor-induced osteomalacia, was found to have a fibroblast growth factor-23-secreting phosphaturic mesenchymal tumor in the T-8 vertebral body. En bloc resection was conducted, leading to resolution of her tumor-induced osteomalacia. This case suggests that radical spondylectomy may be beneficial in the management of metabolically or endocrinologically active tumors of the spine.

Original languageEnglish (US)
Pages (from-to)600-604
Number of pages5
JournalJournal of Neurosurgery: Spine
Issue number5
StatePublished - Nov 2009


  • En bloc spondylectomy
  • Osteoporosis
  • Parathyroid hormone
  • Tumor

ASJC Scopus subject areas

  • Surgery
  • Neurology
  • Clinical Neurology


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