Abstract
TGF-β is long considered a "protean" cytokine in cancer, changing its role from anti- to pro-tumorigenic in a context-dependent manner. In this issue of Cell, David et al. use mouse models of pancreatic cancer to shed light on the mechanistic basis of how TGF-β-induced EMT is coupled to either apoptosis or tumor progression.
Original language | English (US) |
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Pages (from-to) | 840-842 |
Number of pages | 3 |
Journal | Cell |
Volume | 164 |
Issue number | 5 |
DOIs | |
State | Published - Feb 25 2016 |
Externally published | Yes |
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)