Emergent responsive neurostimulation in pediatric super-refractory epilepsia partialis continua

Peter N. Hadar; Pranav Nanda; Katherine G. Walsh; John McLaren; Alexandra Geffrey; Mirela Simon; Kristopher Kahle; R. Mark Richardson; Catherine J. Chu

doi:10.1002/acn3.52199

Emergent responsive neurostimulation in pediatric super-refractory epilepsia partialis continua

Peter N. Hadar
, Pranav Nanda
, Katherine G. Walsh
, John McLaren
, Alexandra Geffrey
, Mirela Simon
, Kristopher Kahle
, R. Mark Richardson
, Catherine J. Chu

Research output: Contribution to journal › Article › peer-review

Abstract

Focal status epilepticus, particularly the motor variant of epilepsia partialis continua (EPC), is a rare condition characterized by near-continuous, chronic focal motor seizures, and associated with poor outcomes. Medications, including anesthetics, are often unsuccessful. Surgical resection can result in motor deficits. We report a medically complex pediatric case of super-refractory EPC that was successfully managed with combined focal resection and responsive neuromodulation. This case introduces neuromodulation as a treatment modality for this challenging condition.

Original language	English (US)
Pages (from-to)	3320-3327
Number of pages	8
Journal	Annals of Clinical and Translational Neurology
Volume	11
Issue number	12
DOIs	https://doi.org/10.1002/acn3.52199
State	Published - Dec 2024
Externally published	Yes

ASJC Scopus subject areas

General Neuroscience
Clinical Neurology

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title = "Emergent responsive neurostimulation in pediatric super-refractory epilepsia partialis continua",

abstract = "Focal status epilepticus, particularly the motor variant of epilepsia partialis continua (EPC), is a rare condition characterized by near-continuous, chronic focal motor seizures, and associated with poor outcomes. Medications, including anesthetics, are often unsuccessful. Surgical resection can result in motor deficits. We report a medically complex pediatric case of super-refractory EPC that was successfully managed with combined focal resection and responsive neuromodulation. This case introduces neuromodulation as a treatment modality for this challenging condition.",

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AU - Hadar, Peter N.

AU - Nanda, Pranav

AU - Walsh, Katherine G.

AU - McLaren, John

AU - Geffrey, Alexandra

AU - Simon, Mirela

AU - Kahle, Kristopher

AU - Richardson, R. Mark

AU - Chu, Catherine J.

PY - 2024/12

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AB - Focal status epilepticus, particularly the motor variant of epilepsia partialis continua (EPC), is a rare condition characterized by near-continuous, chronic focal motor seizures, and associated with poor outcomes. Medications, including anesthetics, are often unsuccessful. Surgical resection can result in motor deficits. We report a medically complex pediatric case of super-refractory EPC that was successfully managed with combined focal resection and responsive neuromodulation. This case introduces neuromodulation as a treatment modality for this challenging condition.

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JO - Annals of Clinical and Translational Neurology

JF - Annals of Clinical and Translational Neurology

IS - 12

ER -

Emergent responsive neurostimulation in pediatric super-refractory epilepsia partialis continua

Abstract

ASJC Scopus subject areas

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