Elevated Serum IL-8 Levels in Ataxia Telangiectasia

Sharon A. McGrath-Morrow, J. Michael Collaco, Thomas O. Crawford, Kathryn A. Carson, Maureen A. Lefton-Greif, Pamela Zeitlin, Howard M. Lederman

Research output: Contribution to journalArticlepeer-review

36 Scopus citations


Serum interleukin (IL)-8 levels were measured in 50 patients with ataxia telangiectasia (A-T) and 22 without A-T. In a cross-sectional study, the geometric mean of IL-8 level was significantly higher in the patients with A-T (P <.0001). Elevated serum IL-8 levels in patients with A-T suggest that systemic inflammation may contribute to the disease phenotype.

Original languageEnglish (US)
Pages (from-to)682-684.e1
JournalJournal of Pediatrics
Issue number4
StatePublished - Apr 2010

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


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