Efficient epimerization of pyrene and other aromatic C-nucleosides with trifluoroacetic acid in dichloromethane

Yu Lin Jiang; James T. Stivers

doi:10.1016/S0040-4039(02)02481-4

Efficient epimerization of pyrene and other aromatic C-nucleosides with trifluoroacetic acid in dichloromethane

Yu Lin Jiang, James T. Stivers

School of Medicine

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

Trifluoroacetic acid has been found to be an efficient and non-oxidative catalyst for the epimerization of pyrene and other C-nucleosides in dichloromethane at ambient temperature. Aspects of the epimerization mechanism are also elucidated.

Original language	English (US)
Pages (from-to)	85-88
Number of pages	4
Journal	Tetrahedron Letters
Volume	44
Issue number	1
DOIs	https://doi.org/10.1016/S0040-4039(02)02481-4
State	Published - Jan 1 2003

Keywords

C-nucleosides
Epimerization
Pyrene nucleoside
Trifluoroacetic acid and dichloromethane

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4039(02)02481-4

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title = "Efficient epimerization of pyrene and other aromatic C-nucleosides with trifluoroacetic acid in dichloromethane",

abstract = "Trifluoroacetic acid has been found to be an efficient and non-oxidative catalyst for the epimerization of pyrene and other C-nucleosides in dichloromethane at ambient temperature. Aspects of the epimerization mechanism are also elucidated.",

keywords = "C-nucleosides, Epimerization, Pyrene nucleoside, Trifluoroacetic acid and dichloromethane",

author = "Jiang, {Yu Lin} and Stivers, {James T.}",

note = "Funding Information: This work was supported by National Institutes of Health Research Grant RO1GM56834 (J.T.S.). Funding Information: This work was supported by NIH grant RO1 GM56834 (J.T.S.). ",

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T1 - Efficient epimerization of pyrene and other aromatic C-nucleosides with trifluoroacetic acid in dichloromethane

AU - Jiang, Yu Lin

AU - Stivers, James T.

N1 - Funding Information: This work was supported by National Institutes of Health Research Grant RO1GM56834 (J.T.S.). Funding Information: This work was supported by NIH grant RO1 GM56834 (J.T.S.).

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Y1 - 2003/1/1

N2 - Trifluoroacetic acid has been found to be an efficient and non-oxidative catalyst for the epimerization of pyrene and other C-nucleosides in dichloromethane at ambient temperature. Aspects of the epimerization mechanism are also elucidated.

AB - Trifluoroacetic acid has been found to be an efficient and non-oxidative catalyst for the epimerization of pyrene and other C-nucleosides in dichloromethane at ambient temperature. Aspects of the epimerization mechanism are also elucidated.

KW - C-nucleosides

KW - Epimerization

KW - Pyrene nucleoside

KW - Trifluoroacetic acid and dichloromethane

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Efficient epimerization of pyrene and other aromatic C-nucleosides with trifluoroacetic acid in dichloromethane

Abstract

Keywords

ASJC Scopus subject areas

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