Efficacy of ICD/CRT-D Remote Monitoring in Patients With HFrEF: a Bayesian Meta-analysis of Randomized Controlled Trials

Ahmad Al-Abdouh, Mohammed Mhanna, Mohammad As Sayaideh, Mahmoud Barbarawi, Waiel Abusnina, Ahmad Jabri, Hossam Alzu’bi, Anan Abu Rmilah, Ikram Ul Haq, Ashish Kumar, Taha Ahmed, Erin D. Michos, Gurukripa N. Kowlgi, Abhishek Deshmukh

Research output: Contribution to journalReview articlepeer-review

Abstract

Purpose of Review: To evaluate remote monitoring using implantable cardioverter-defibrillator (ICD) or cardiac resynchronization therapy defibrillator (CRT-D) devices as an adjunctive tool to the traditional care of patients with heart failure (HF). Recent Findings: We included 11 trials encompassing 5965 patients. Absolute risk difference (ARD) with 95% credible interval (CrI) was estimated. Pooled (posterior) risk difference was computed using Bayesian hierarchical methods. The ARD for mortality was centered at − 0.01 (95% CrI: − 0.03; 0.01, Tau: 0.02), with an 82% probability of ARD of ICD/CRT-D remote monitoring with respect to control being less than 0. The ARD for cardiovascular mortality was centered at − 0.03 (95% CrI: − 0.11; 0.05, Tau: 0.10), with an 84% probability of ARD of ICD/CRT-D remote monitoring with respect to control being less than 0. Summary: ICD/CRT-D remote monitoring in patients with HF is associated with a higher probability of reduced all-cause and cardiovascular mortality compared with standard care alone.

Original languageEnglish (US)
Pages (from-to)435-444
Number of pages10
JournalCurrent heart failure reports
Volume19
Issue number6
DOIs
StatePublished - Dec 2022

Keywords

  • Cardiac resynchronization therapy
  • Heart failure
  • Implantable cardioverter-defibrillators
  • Mortality
  • Remote monitoring

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)
  • Emergency Medicine

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