Effects of polycystic ovary syndrome on health-related quality of life

Krishna Upadhya, Maria Trent

Research output: Contribution to journalReview articlepeer-review

8 Scopus citations


Polycystic ovary syndrome (PCOS) is a common endocrine disorder affecting 5-10% of women of reproductive age. The health risks associated with PCOS include infertility, diabetes, metabolic syndrome and endometrial cancer. In this article, we review the tools used to assess health-related quality of life (HRQL) and the current state of knowledge of the effects of PCOS on HRQL in adult women and adolescent girls. A significant body of evidence-consistently demonstrates that PCOS has a negative impact on women's HRQL. This impact does not necessarily correlate with clinical measures of disease severity. There is evidence that the effect on HRQL may be mediated by obesity, infertility concerns and menstrual dysfunction. Cross-cultural studies suggest that the effect of PCOS on the HRQL of an individual patient may be specific to the perception, values and culture of that patient.

Original languageEnglish (US)
Pages (from-to)597-603
Number of pages7
JournalExpert Review of Pharmacoeconomics and Outcomes Research
Issue number6
StatePublished - Dec 2007


  • Health-related quality of life
  • Hirsutism
  • Infertility
  • Menstrual disorder
  • Obesity
  • Patient-centered approach
  • Polycystic ovary syndrome

ASJC Scopus subject areas

  • Health Policy
  • Pharmacology (medical)


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