Effects of infant sex on mother-to-child transmission of HIV-1 according to timing of infection in Zimbabwe

Ellen G. Piwoz; Jean H. Humphrey; Edmore T. Marinda; Kuda Mutasa; Lawrence H. Moulton; Peter J. Iliff

doi:10.1097/01.aids.0000247123.04703.6e

Effects of infant sex on mother-to-child transmission of HIV-1 according to timing of infection in Zimbabwe

Ellen G. Piwoz, Jean H. Humphrey, Edmore T. Marinda, Kuda Mutasa, Lawrence H. Moulton, Peter J. Iliff

Bloomberg School of Public Health

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

We examined the relationship between sex and the risk of intrauterine, intrapartum and postnatal HIV transmission among 4495 infants born to HIV-infected mothers in Harare, Zimbabwe. Intrauterine transmission was 8.6%, and consistent with other studies was higher among girl than boy infants (AOR 1.53; 95% CI 1.23-1.91). Unlike previous studies, we observed no independent effect of infant sex on intrapartum or breastfeeding-associated HIV transmission. Sex-specific postnatal prevention strategies are not warranted in this population.

Original language	English (US)
Pages (from-to)	1981-1984
Number of pages	4
Journal	AIDS
Volume	20
Issue number	15
DOIs	https://doi.org/10.1097/01.aids.0000247123.04703.6e
State	Published - Oct 2006

ASJC Scopus subject areas

Immunology and Allergy
Immunology
Infectious Diseases

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title = "Effects of infant sex on mother-to-child transmission of HIV-1 according to timing of infection in Zimbabwe",

abstract = "We examined the relationship between sex and the risk of intrauterine, intrapartum and postnatal HIV transmission among 4495 infants born to HIV-infected mothers in Harare, Zimbabwe. Intrauterine transmission was 8.6%, and consistent with other studies was higher among girl than boy infants (AOR 1.53; 95% CI 1.23-1.91). Unlike previous studies, we observed no independent effect of infant sex on intrapartum or breastfeeding-associated HIV transmission. Sex-specific postnatal prevention strategies are not warranted in this population.",

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AU - Piwoz, Ellen G.

AU - Humphrey, Jean H.

AU - Marinda, Edmore T.

AU - Mutasa, Kuda

AU - Moulton, Lawrence H.

AU - Iliff, Peter J.

PY - 2006/10

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N2 - We examined the relationship between sex and the risk of intrauterine, intrapartum and postnatal HIV transmission among 4495 infants born to HIV-infected mothers in Harare, Zimbabwe. Intrauterine transmission was 8.6%, and consistent with other studies was higher among girl than boy infants (AOR 1.53; 95% CI 1.23-1.91). Unlike previous studies, we observed no independent effect of infant sex on intrapartum or breastfeeding-associated HIV transmission. Sex-specific postnatal prevention strategies are not warranted in this population.

AB - We examined the relationship between sex and the risk of intrauterine, intrapartum and postnatal HIV transmission among 4495 infants born to HIV-infected mothers in Harare, Zimbabwe. Intrauterine transmission was 8.6%, and consistent with other studies was higher among girl than boy infants (AOR 1.53; 95% CI 1.23-1.91). Unlike previous studies, we observed no independent effect of infant sex on intrapartum or breastfeeding-associated HIV transmission. Sex-specific postnatal prevention strategies are not warranted in this population.

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Effects of infant sex on mother-to-child transmission of HIV-1 according to timing of infection in Zimbabwe

Abstract

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