Effects of controlled-released morphine on quality of life for cancer pain.

B. Ferrell, C. Wisdom, C. Wenzl, J. Brown

Research output: Contribution to journalArticlepeer-review

85 Scopus citations


Oncology nursing is concerned with pain relief and overall Quality of Life (QOL). The purpose of this study was to determine the effects of controlled-release morphine on QOL for patients with cancer. Eighty-three subjects were randomly assigned in a clinical trial of short-acting versus controlled-release analgesia (MS Contin, Purdue Frederick Co., Norwalk, CT). Data was collected in a repeated measures design every 2 weeks for 6 weeks yielding a total of 240 visits. Five instruments were used to assess QOL, pain, and functional status. Study findings indicate improved pain management with controlled-release MS Contin and important nursing implications for the management of analgesia-induced gastrointestinal symptoms. Through appropriate pain management with pain therapies such as controlled-release analgesia, nurses can greatly enhance QOL for the patient with cancer.

Original languageEnglish (US)
Pages (from-to)521-526
Number of pages6
JournalOncology nursing forum
Issue number4
StatePublished - Jul 1989

ASJC Scopus subject areas

  • Oncology(nursing)


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