Effects of aging on the diurnal pattern of water intake in rats

Rebecca D. Burwell; Julia Whealin; Michela Gallagher

doi:10.1016/0163-1047(92)90468-J

Effects of aging on the diurnal pattern of water intake in rats

Rebecca D. Burwell, Julia Whealin, Michela Gallagher

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

This study was undertaken to confirm previous findings that Long-Evans rats exhibit age-related changes in the diurnal/nocturnal distribution of water intake and to examine the circadian pattern of these age-related changes. Twenty-one aged and 10 young pathogen-free rats were continuously monitored for water consumption over 12:12 h light/dark cycles. ANOVA, profile analysis, and cosinor analysis each demonstrated that aged rats differed from young rats. The age-related changes in circadian pattern can be described as a blunted rhythm (decreased amplitude) and an altered timing of peak activity (advanced acrophase). These differences, however, were only apparent in a subset of aged rats with the remaining aged rats exhibiting a circadian pattern indistinguishable from that of the young group.

Original language	English (US)
Pages (from-to)	196-203
Number of pages	8
Journal	Behavioral and Neural Biology
Volume	58
Issue number	3
DOIs	https://doi.org/10.1016/0163-1047(92)90468-J
State	Published - Nov 1992
Externally published	Yes

ASJC Scopus subject areas

Physiology

Access to Document

10.1016/0163-1047(92)90468-J

Cite this

@article{9101a3a0325741c899cc8c23a821cb46,

title = "Effects of aging on the diurnal pattern of water intake in rats",

abstract = "This study was undertaken to confirm previous findings that Long-Evans rats exhibit age-related changes in the diurnal/nocturnal distribution of water intake and to examine the circadian pattern of these age-related changes. Twenty-one aged and 10 young pathogen-free rats were continuously monitored for water consumption over 12:12 h light/dark cycles. ANOVA, profile analysis, and cosinor analysis each demonstrated that aged rats differed from young rats. The age-related changes in circadian pattern can be described as a blunted rhythm (decreased amplitude) and an altered timing of peak activity (advanced acrophase). These differences, however, were only apparent in a subset of aged rats with the remaining aged rats exhibiting a circadian pattern indistinguishable from that of the young group.",

author = "Burwell, {Rebecca D.} and Julia Whealin and Michela Gallagher",

note = "Funding Information: 1 Correspondence and reprint requests should be addressed to Michela Gallagher. Research supported by NIA grant AG09973, NIMH Grant MH39180, NIMH Research Scientist Development Award KO2-MH100406 to M.G., and a NSF Predoctoral Fellowship Award to R.B. The authors gratefully acknowledge Landon Whitt, Jr. for technical assistance and Gregory M. Straw, M.D., for statistical assistance with the cosinor analyses. Copyright: Copyright 2014 Elsevier B.V., All rights reserved.",

year = "1992",

month = nov,

doi = "10.1016/0163-1047(92)90468-J",

language = "English (US)",

volume = "58",

pages = "196--203",

journal = "Communications in behavioral biology. Part A: [Original articles]",

issn = "1074-7427",

publisher = "Academic Press Inc.",

number = "3",

}

TY - JOUR

T1 - Effects of aging on the diurnal pattern of water intake in rats

AU - Burwell, Rebecca D.

AU - Whealin, Julia

AU - Gallagher, Michela

N1 - Funding Information: 1 Correspondence and reprint requests should be addressed to Michela Gallagher. Research supported by NIA grant AG09973, NIMH Grant MH39180, NIMH Research Scientist Development Award KO2-MH100406 to M.G., and a NSF Predoctoral Fellowship Award to R.B. The authors gratefully acknowledge Landon Whitt, Jr. for technical assistance and Gregory M. Straw, M.D., for statistical assistance with the cosinor analyses. Copyright: Copyright 2014 Elsevier B.V., All rights reserved.

PY - 1992/11

Y1 - 1992/11

N2 - This study was undertaken to confirm previous findings that Long-Evans rats exhibit age-related changes in the diurnal/nocturnal distribution of water intake and to examine the circadian pattern of these age-related changes. Twenty-one aged and 10 young pathogen-free rats were continuously monitored for water consumption over 12:12 h light/dark cycles. ANOVA, profile analysis, and cosinor analysis each demonstrated that aged rats differed from young rats. The age-related changes in circadian pattern can be described as a blunted rhythm (decreased amplitude) and an altered timing of peak activity (advanced acrophase). These differences, however, were only apparent in a subset of aged rats with the remaining aged rats exhibiting a circadian pattern indistinguishable from that of the young group.

AB - This study was undertaken to confirm previous findings that Long-Evans rats exhibit age-related changes in the diurnal/nocturnal distribution of water intake and to examine the circadian pattern of these age-related changes. Twenty-one aged and 10 young pathogen-free rats were continuously monitored for water consumption over 12:12 h light/dark cycles. ANOVA, profile analysis, and cosinor analysis each demonstrated that aged rats differed from young rats. The age-related changes in circadian pattern can be described as a blunted rhythm (decreased amplitude) and an altered timing of peak activity (advanced acrophase). These differences, however, were only apparent in a subset of aged rats with the remaining aged rats exhibiting a circadian pattern indistinguishable from that of the young group.

UR - http://www.scopus.com/inward/record.url?scp=0027052873&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0027052873&partnerID=8YFLogxK

U2 - 10.1016/0163-1047(92)90468-J

DO - 10.1016/0163-1047(92)90468-J

M3 - Article

C2 - 1456941

AN - SCOPUS:0027052873

SN - 1074-7427

VL - 58

SP - 196

EP - 203

JO - Communications in behavioral biology. Part A: [Original articles]

JF - Communications in behavioral biology. Part A: [Original articles]

IS - 3

ER -

Effects of aging on the diurnal pattern of water intake in rats

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this