Effective weight loss management with endoscopic gastric plication using StomaphyX device: Is it achievable?

Sharon K. Ong'Uti, Gezzer Ortega, Michael T. Onwugbufor, Gabriel D. Ivey, Terrence M. Fullum, Daniel D. Tran

Research output: Contribution to journalArticlepeer-review


Background: Despite the effectiveness of Roux-en-Y gastric bypass (RYGB) in promoting excess weight loss, 40% of the patients regain weight. Endoscopic gastric plication (EGP) using the StomaphyX device can serve as a less-invasive procedure for promoting the loss of regained weight. Our objective was to evaluate the effectiveness of the StomaphyX device in sustaining ongoing weight loss in patients who have regained weight after RYGB at the Division of Minimally Invasive and Bariatric Surgery, Howard University Hospital. Methods: We performed a retrospective chart review of patients undergoing EGP using the StomaphyX device from April 2008 to May 2010. The patient demographics and clinical information were assessed. Effective weight loss and the proportion of weight lost after EGP relative to the weight regained after achieving the lowest weight following RYGB was calculated. Results: A total of 27 patients underwent EGP using the StomaphyX device; of these, most were women (n = 25, 93%) and black (n = 14, 52%), followed by white (n = 11, 42%), and Hispanic (n = 1, 4%). The median interval between RYGB and EGP was 6 years, with an interquartile range of 5-8 years. After the EGP procedure, the median effective weight loss was 37% (interquartile range 24-61%). Of the 27 patients, 18 had ≥6 months of follow-up after EGP. Eleven patients had achieved their lowest weight at 1-3 months, 7 at 6 months, and 3 at 12 months. Of the 18 patients, 13 (72%) experienced an increase in weight after achieving their lowest weight after EGP. Conclusion: The use of the StomaphyX device achieved the maximum effective weight loss during the 1-6-month period after EGP.

Original languageEnglish (US)
Pages (from-to)113-117
Number of pages5
JournalSurgery for Obesity and Related Diseases
Issue number1
StatePublished - Jan 2013
Externally publishedYes


  • Endoscopic gastric plication
  • Obesity
  • Revision surgery
  • Roux-en-Y gastric bypass
  • StomaphyX
  • Weight regain

ASJC Scopus subject areas

  • Surgery


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