Effective removal of albumin from serum

David A. Colantonio, Christy Dunkinson, Diane E. Bovenkamp, Jennifer E. Van Eyk

Research output: Contribution to journalArticlepeer-review

76 Scopus citations


The protein constituents of serum can range from grams to picograms per liter, making it technically difficult to achieve in-depth proteomic analysis. Removal of highly abundant proteins, such as albumin, coupled to powerful protein separation methods is required for increased sample load, thus facilitating detection and identification of low-abundant proteins. We report here a chemical-based extraction method for the effective and specific removal of albumin from serum.

Original languageEnglish (US)
Pages (from-to)3831-3835
Number of pages5
Issue number15
StatePublished - Oct 2005
Externally publishedYes


  • 2-DE
  • Albumin
  • Enrichment
  • Serum proteome

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology


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