Abstract
A randomized controlled trial was conducted in 395 infants aged 9-12 months to determine the effect of Vitamin A supplementation on concurrently administered measles vaccine. Antibody response was measured using the plaque reduction neutralization assay. No statistically significant differences were demonstrated between the immune response in Vitamin A supplemented and unsupplemented children. Unlike some recent studies, we were unable to demonstrate an immune enhancing effect of Vitamin A supplementation. On the contrary, among children who were given Vitamin A, a lower, but statistically non-significant, proportion had protective antibody levels 6 months after vaccination.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 2418-2420 |
| Number of pages | 3 |
| Journal | Vaccine |
| Volume | 21 |
| Issue number | 19-20 |
| DOIs | |
| State | Published - Jun 2 2003 |
| Externally published | Yes |
Keywords
- Immune response
- Measles vaccine
- Vitamin A
ASJC Scopus subject areas
- Molecular Medicine
- Immunology and Microbiology(all)
- veterinary(all)
- Public Health, Environmental and Occupational Health
- Infectious Diseases