Effect of Pharmacologic Prophylaxis on Venous Thromboembolism After Radical Prostatectomy: The PREVENTER Randomized Clinical Trial

Hiten D. Patel; Farzana A. Faisal; Bruce Trock; Gregory A. Joice; Zeyad R. Schwen; Phillip Martin Pierorazio; Michael Johnson; Trinity Bivalacqua; Misop Han; Michael Gorin; H Ballentine Carter; Alan Partin; Christian P. Pavlovich; Mohamad E. Allaf

doi:10.1016/j.eururo.2020.05.001

Effect of Pharmacologic Prophylaxis on Venous Thromboembolism After Radical Prostatectomy: The PREVENTER Randomized Clinical Trial

Hiten D. Patel, Farzana A. Faisal, Bruce Trock, Gregory A. Joice, Zeyad R. Schwen, Phillip Martin Pierorazio, Michael Johnson, Trinity Bivalacqua, Misop Han, Michael Gorin, H Ballentine Carter, Alan Partin, Christian P. Pavlovich, Mohamad E. Allaf

School of Medicine

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

In the Prevention of Venous Thromboembolism Following Radical Prostatectomy (PREVENTER) randomized trial, pharmacologic prophylaxis did not reduce the rate of symptomatic (relative risk [RR] 0.40 [95% confidence interval {CI} 0.08–2.03], p = 0.267) or overall (RR 0.97 [95% CI 0.25–3.81], p = 0.967) venous thromboembolism significantly. There was no increase in adverse events including symptomatic lymphoceles or bleeding.

Original language	English (US)
Pages (from-to)	360-368
Number of pages	9
Journal	European Urology
Volume	78
Issue number	3
DOIs	https://doi.org/10.1016/j.eururo.2020.05.001
State	Published - Sep 2020

Keywords

Clinical trial
Evidence-based medicine
Quality improvement
Radical prostatectomy
Surgery
Venous thromboembolism

ASJC Scopus subject areas

Urology

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10.1016/j.eururo.2020.05.001

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Patel, H. D., Faisal, F. A., Trock, B., Joice, G. A., Schwen, Z. R., Pierorazio, P. M., Johnson, M., Bivalacqua, T., Han, M., Gorin, M., Carter, H. B., Partin, A., Pavlovich, C. P., & Allaf, M. E. (2020). Effect of Pharmacologic Prophylaxis on Venous Thromboembolism After Radical Prostatectomy: The PREVENTER Randomized Clinical Trial. European Urology, 78(3), 360-368. https://doi.org/10.1016/j.eururo.2020.05.001

Patel, HD, Faisal, FA, Trock, B, Joice, GA, Schwen, ZR, Pierorazio, PM, Johnson, M, Bivalacqua, T, Han, M, Gorin, M, Carter, HB, Partin, A, Pavlovich, CP & Allaf, ME 2020, 'Effect of Pharmacologic Prophylaxis on Venous Thromboembolism After Radical Prostatectomy: The PREVENTER Randomized Clinical Trial', European Urology, vol. 78, no. 3, pp. 360-368. https://doi.org/10.1016/j.eururo.2020.05.001

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title = "Effect of Pharmacologic Prophylaxis on Venous Thromboembolism After Radical Prostatectomy: The PREVENTER Randomized Clinical Trial",

abstract = "In the Prevention of Venous Thromboembolism Following Radical Prostatectomy (PREVENTER) randomized trial, pharmacologic prophylaxis did not reduce the rate of symptomatic (relative risk [RR] 0.40 [95% confidence interval {CI} 0.08–2.03], p = 0.267) or overall (RR 0.97 [95% CI 0.25–3.81], p = 0.967) venous thromboembolism significantly. There was no increase in adverse events including symptomatic lymphoceles or bleeding.",

keywords = "Clinical trial, Evidence-based medicine, Quality improvement, Radical prostatectomy, Surgery, Venous thromboembolism",

author = "Patel, {Hiten D.} and Faisal, {Farzana A.} and Bruce Trock and Joice, {Gregory A.} and Schwen, {Zeyad R.} and Pierorazio, {Phillip Martin} and Michael Johnson and Trinity Bivalacqua and Misop Han and Michael Gorin and Carter, {H Ballentine} and Alan Partin and Pavlovich, {Christian P.} and Allaf, {Mohamad E.}",

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year = "2020",

month = sep,

doi = "10.1016/j.eururo.2020.05.001",

language = "English (US)",

volume = "78",

pages = "360--368",

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T2 - The PREVENTER Randomized Clinical Trial

AU - Patel, Hiten D.

AU - Faisal, Farzana A.

AU - Trock, Bruce

AU - Joice, Gregory A.

AU - Schwen, Zeyad R.

AU - Pierorazio, Phillip Martin

AU - Johnson, Michael

AU - Bivalacqua, Trinity

AU - Han, Misop

AU - Gorin, Michael

AU - Carter, H Ballentine

AU - Partin, Alan

AU - Pavlovich, Christian P.

AU - Allaf, Mohamad E.

PY - 2020/9

Y1 - 2020/9

N2 - In the Prevention of Venous Thromboembolism Following Radical Prostatectomy (PREVENTER) randomized trial, pharmacologic prophylaxis did not reduce the rate of symptomatic (relative risk [RR] 0.40 [95% confidence interval {CI} 0.08–2.03], p = 0.267) or overall (RR 0.97 [95% CI 0.25–3.81], p = 0.967) venous thromboembolism significantly. There was no increase in adverse events including symptomatic lymphoceles or bleeding.

AB - In the Prevention of Venous Thromboembolism Following Radical Prostatectomy (PREVENTER) randomized trial, pharmacologic prophylaxis did not reduce the rate of symptomatic (relative risk [RR] 0.40 [95% confidence interval {CI} 0.08–2.03], p = 0.267) or overall (RR 0.97 [95% CI 0.25–3.81], p = 0.967) venous thromboembolism significantly. There was no increase in adverse events including symptomatic lymphoceles or bleeding.

KW - Clinical trial

KW - Evidence-based medicine

KW - Quality improvement

KW - Radical prostatectomy

KW - Surgery

KW - Venous thromboembolism

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AN - SCOPUS:85084850948

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VL - 78

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EP - 368

JO - European Urology

JF - European Urology

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ER -

Effect of Pharmacologic Prophylaxis on Venous Thromboembolism After Radical Prostatectomy: The PREVENTER Randomized Clinical Trial

Abstract

Keywords

ASJC Scopus subject areas

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