Effect of fractionated doses of pions on normal tissues: Part II. Mouse jejunum

Lester J. Peters; H. Rodney Withers; Kathryn A. Mason; J. F. Dicello

doi:10.1016/0360-3016(80)90250-3

Effect of fractionated doses of pions on normal tissues: Part II. Mouse jejunum

Lester J. Peters, H. Rodney Withers, Kathryn A. Mason, J. F. Dicello

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

The biological efficiency of π-mesons relatise to ⁶⁰Co γ-rays for jejunal crypt cell lethality increased with decreasing size of dose fractions. At fractional doses of 450 rad of γ-ray, the RBE was ∼1.75. The survival of crypt colony-forming cells varied as a function of the stage in the division cycle at which they were irradiated, but this variation was less with π-mesons than with γ-rays.

Original language	English (US)
Pages (from-to)	1667-1669
Number of pages	3
Journal	International journal of radiation oncology, biology, physics
Volume	6
Issue number	12
DOIs	https://doi.org/10.1016/0360-3016(80)90250-3
State	Published - Dec 1980
Externally published	Yes

Keywords

Division-cycle
Intestine
Pions
Radiotherapy
Relative biological efficiency

ASJC Scopus subject areas

Radiation
Oncology
Radiology Nuclear Medicine and imaging
Cancer Research

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10.1016/0360-3016(80)90250-3

Cite this

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title = "Effect of fractionated doses of pions on normal tissues: Part II. Mouse jejunum",

abstract = "The biological efficiency of π-mesons relatise to 60Co γ-rays for jejunal crypt cell lethality increased with decreasing size of dose fractions. At fractional doses of 450 rad of γ-ray, the RBE was ∼1.75. The survival of crypt colony-forming cells varied as a function of the stage in the division cycle at which they were irradiated, but this variation was less with π-mesons than with γ-rays.",

keywords = "Division-cycle, Intestine, Pions, Radiotherapy, Relative biological efficiency",

author = "Peters, {Lester J.} and {Rodney Withers}, H. and Mason, {Kathryn A.} and Dicello, {J. F.}",

note = "Funding Information: This investigation was supported in part b) research grant CA-I 1135 and CA-06294, awarded by the National Cancer Institute, DHEW. *Present Address: The Institute of Radiotherap),. The Prince of Wales Hospital. Randwick. N.S.W. 2031, Australia.",

year = "1980",

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doi = "10.1016/0360-3016(80)90250-3",

language = "English (US)",

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pages = "1667--1669",

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T1 - Effect of fractionated doses of pions on normal tissues

T2 - Part II. Mouse jejunum

AU - Peters, Lester J.

AU - Rodney Withers, H.

AU - Mason, Kathryn A.

AU - Dicello, J. F.

N1 - Funding Information: This investigation was supported in part b) research grant CA-I 1135 and CA-06294, awarded by the National Cancer Institute, DHEW. *Present Address: The Institute of Radiotherap),. The Prince of Wales Hospital. Randwick. N.S.W. 2031, Australia.

PY - 1980/12

Y1 - 1980/12

N2 - The biological efficiency of π-mesons relatise to 60Co γ-rays for jejunal crypt cell lethality increased with decreasing size of dose fractions. At fractional doses of 450 rad of γ-ray, the RBE was ∼1.75. The survival of crypt colony-forming cells varied as a function of the stage in the division cycle at which they were irradiated, but this variation was less with π-mesons than with γ-rays.

AB - The biological efficiency of π-mesons relatise to 60Co γ-rays for jejunal crypt cell lethality increased with decreasing size of dose fractions. At fractional doses of 450 rad of γ-ray, the RBE was ∼1.75. The survival of crypt colony-forming cells varied as a function of the stage in the division cycle at which they were irradiated, but this variation was less with π-mesons than with γ-rays.

KW - Division-cycle

KW - Intestine

KW - Pions

KW - Radiotherapy

KW - Relative biological efficiency

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JF - International journal of radiation oncology, biology, physics

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Effect of fractionated doses of pions on normal tissues: Part II. Mouse jejunum

Abstract

Keywords

ASJC Scopus subject areas

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