Edema Associated With Ibuprofen Therapy

Robert T. Schooley; Philip F. Wagley; Paul S. Lietman

doi:10.1001/jama.1977.03270430058021

Edema Associated With Ibuprofen Therapy

Robert T. Schooley, Philip F. Wagley, Paul S. Lietman

Research output: Contribution to journal › Article › peer-review

38 Scopus citations

Abstract

A 15-kg weight gain developed in a patient during the third week of ibuprofen therapy. The edema disappeared with discontinuation of the drug regimen and did not reappear during a subsequent six-month observation period. It should be recognized that ibuprofen may be associated with salt and water retention in the same fashion as previously described with phenylbutazone and indomethacin.

Original language	English (US)
Pages (from-to)	1716-1717
Number of pages	2
Journal	JAMA: The Journal of the American Medical Association
Volume	237
Issue number	16
DOIs	https://doi.org/10.1001/jama.1977.03270430058021
State	Published - Apr 18 1977
Externally published	Yes

ASJC Scopus subject areas

General Medicine

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10.1001/jama.1977.03270430058021

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title = "Edema Associated With Ibuprofen Therapy",

abstract = "A 15-kg weight gain developed in a patient during the third week of ibuprofen therapy. The edema disappeared with discontinuation of the drug regimen and did not reappear during a subsequent six-month observation period. It should be recognized that ibuprofen may be associated with salt and water retention in the same fashion as previously described with phenylbutazone and indomethacin.",

author = "Schooley, {Robert T.} and Wagley, {Philip F.} and Lietman, {Paul S.}",

note = "Funding Information: ver)developedwithin24to42hours, andfourbecamesymptomaticafter 55to80hoursofadrenalsteroiddep¬ rivation. Ourpatientenduredbedandchair activitywithoutdifficultyuntilabout 150 hours hadelapsed.Itispossible thatonedeterminantofhersurvival washerminimalactivity. ThisstudywassupportedinpartbyClinical CancerResearchCentergrantCA-07177and grant IR25-CA17952 from the National Cancer Institute.",

year = "1977",

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day = "18",

doi = "10.1001/jama.1977.03270430058021",

language = "English (US)",

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pages = "1716--1717",

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T1 - Edema Associated With Ibuprofen Therapy

AU - Schooley, Robert T.

AU - Wagley, Philip F.

AU - Lietman, Paul S.

N1 - Funding Information: ver)developedwithin24to42hours, andfourbecamesymptomaticafter 55to80hoursofadrenalsteroiddep¬ rivation. Ourpatientenduredbedandchair activitywithoutdifficultyuntilabout 150 hours hadelapsed.Itispossible thatonedeterminantofhersurvival washerminimalactivity. ThisstudywassupportedinpartbyClinical CancerResearchCentergrantCA-07177and grant IR25-CA17952 from the National Cancer Institute.

PY - 1977/4/18

Y1 - 1977/4/18

N2 - A 15-kg weight gain developed in a patient during the third week of ibuprofen therapy. The edema disappeared with discontinuation of the drug regimen and did not reappear during a subsequent six-month observation period. It should be recognized that ibuprofen may be associated with salt and water retention in the same fashion as previously described with phenylbutazone and indomethacin.

AB - A 15-kg weight gain developed in a patient during the third week of ibuprofen therapy. The edema disappeared with discontinuation of the drug regimen and did not reappear during a subsequent six-month observation period. It should be recognized that ibuprofen may be associated with salt and water retention in the same fashion as previously described with phenylbutazone and indomethacin.

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DO - 10.1001/jama.1977.03270430058021

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AN - SCOPUS:0017664599

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JO - JAMA: The Journal of the American Medical Association

JF - JAMA: The Journal of the American Medical Association

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ER -

Edema Associated With Ibuprofen Therapy

Abstract

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