Early-life influences on obesity: From preconception to adolescence

Mark L. Wahlqvist; Stephen A. Krawetz; Nico S. Rizzo; Maria Gloria Dominguez-Bello; Linda M. Szymanski; Shari Barkin; Ann Yatkine; Robert A. Waterland; Julie A. Mennella; Mina Desai; Michael G. Ross; Nancy F. Krebs; Bridget E. Young; Jane Wardle; Christiane D. Wrann; John G. Kral

doi:10.1111/nyas.12778

Early-life influences on obesity: From preconception to adolescence

Mark L. Wahlqvist, Stephen A. Krawetz, Nico S. Rizzo, Maria Gloria Dominguez-Bello, Linda M. Szymanski, Shari Barkin, Ann Yatkine, Robert A. Waterland, Julie A. Mennella, Mina Desai, Michael G. Ross, Nancy F. Krebs, Bridget E. Young, Jane Wardle, Christiane D. Wrann, John G. Kral

School of Medicine

Research output: Contribution to journal › Article › peer-review

30 Scopus citations

Abstract

The double burden of under- and overnutrition profoundly affects human health globally. According to the World Health Organization, obesity and diabetes rates have almost doubled worldwide since 1980, and, in 2011, more than 40 million children under 5 years of age were overweight. Ecologic factors, parental genetics and fitness, and the intrauterine environment significantly influence the likelihood of offspring developing the dysmetabolic diathesis of obesity. This report examines the effects of these factors, including preconception, intrauterine and postnatal energy balance affecting programming of transgenerational transmission, and development of chronic diseases later in life-in particular, diabesity and its comorbidities.

Original language	English (US)
Pages (from-to)	1-28
Number of pages	28
Journal	Annals of the New York Academy of Sciences
Volume	1347
Issue number	1
DOIs	https://doi.org/10.1111/nyas.12778
State	Published - 2015

Keywords

Breast feeding
Diabesity
Econutritional
Epigenetics
Exercise
Microbiome
Nutrition
Obesity
Taste preferences

ASJC Scopus subject areas

General Neuroscience
General Biochemistry, Genetics and Molecular Biology
History and Philosophy of Science

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10.1111/nyas.12778

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Wahlqvist, M. L., Krawetz, S. A., Rizzo, N. S., Dominguez-Bello, M. G., Szymanski, L. M., Barkin, S., Yatkine, A., Waterland, R. A., Mennella, J. A., Desai, M., Ross, M. G., Krebs, N. F., Young, B. E., Wardle, J., Wrann, C. D., & Kral, J. G. (2015). Early-life influences on obesity: From preconception to adolescence. Annals of the New York Academy of Sciences, 1347(1), 1-28. https://doi.org/10.1111/nyas.12778

Wahlqvist, ML, Krawetz, SA, Rizzo, NS, Dominguez-Bello, MG, Szymanski, LM, Barkin, S, Yatkine, A, Waterland, RA, Mennella, JA, Desai, M, Ross, MG, Krebs, NF, Young, BE, Wardle, J, Wrann, CD & Kral, JG 2015, 'Early-life influences on obesity: From preconception to adolescence', Annals of the New York Academy of Sciences, vol. 1347, no. 1, pp. 1-28. https://doi.org/10.1111/nyas.12778

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abstract = "The double burden of under- and overnutrition profoundly affects human health globally. According to the World Health Organization, obesity and diabetes rates have almost doubled worldwide since 1980, and, in 2011, more than 40 million children under 5 years of age were overweight. Ecologic factors, parental genetics and fitness, and the intrauterine environment significantly influence the likelihood of offspring developing the dysmetabolic diathesis of obesity. This report examines the effects of these factors, including preconception, intrauterine and postnatal energy balance affecting programming of transgenerational transmission, and development of chronic diseases later in life-in particular, diabesity and its comorbidities.",

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AU - Mennella, Julie A.

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KW - Obesity

KW - Taste preferences

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Early-life influences on obesity: From preconception to adolescence

Abstract

Keywords

ASJC Scopus subject areas

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