Seizure prone gerbils reared under low levels of stimulation had shorter seizure latencies than those given extra stimulation from post-natal days 1-21. They also exhibited prolonged postseizure hyperactivity in the open field whereas the latter did not. This provides new evidence that level of cerebral excitability is, in part, a function of early experience. Further, it suggests that seizure activity and its after effects may be mitigated by manipulating the early experience of seizure prone subjects.
ASJC Scopus subject areas
- Experimental and Cognitive Psychology
- Cognitive Neuroscience
- Behavioral Neuroscience