Dynamics of Gradient Sensing and Chemotaxis

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations


Chemotaxis, the ability of cells to sense external chemical gradients in order to direct movement is essential for the survival of all organisms, from bacteria and amoebae to humans. It requires the coordinated action of several processes, from the sensing of the external chemical to the interpretation of the gradient, to the steering of the cell's motion. Here we review a number of strategies used by cells that allow them to perform these various tasks successfully.

Original languageEnglish (US)
Title of host publicationSystems Cell Biology
PublisherElsevier Inc.
Number of pages6
ISBN (Electronic)9780123944474
ISBN (Print)9780123947963
StatePublished - Jan 1 2016


  • Adaptation
  • Excitable network
  • Global inhibition
  • Incoherent feedforward loop
  • Local excitation
  • Motility
  • Negative feedback
  • Positive feedback
  • Pseudopods
  • Signal amplification

ASJC Scopus subject areas

  • General Medicine


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