Dynamic Brain Connectivity in Resting State Functional MR Imaging

Rozita Jalilianhasanpour, Daniel Ryan, Shruti Agarwal, Elham Beheshtian, Sachin K. Gujar, Jay J. Pillai, Haris I. Sair

Research output: Contribution to journalReview articlepeer-review


Dynamic functional connectivity adds another dimension to resting-state functional MR imaging analysis. In recent years, dynamic functional connectivity has been increasingly used in resting-state functional MR imaging, and several studies have demonstrated that dynamic functional connectivity patterns correlate with different physiologic and pathologic brain states. In fact, evidence suggests that dynamic functional connectivity is a more sensitive marker than static functional connectivity; therefore, it might be a promising tool to add to clinical functional neuroimaging. This article provides a broad overview of dynamic functional connectivity and reviews its general principles, techniques, and potential clinical applications.

Original languageEnglish (US)
Pages (from-to)81-92
Number of pages12
JournalNeuroimaging Clinics of North America
Issue number1
StatePublished - Feb 2021


  • Brain mapping
  • Dynamic connectivity
  • Functional connectivity
  • Resting state MR imaging
  • Rs-fMRI

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology


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