Drug effects and initial severity of symptomatology

Seymour Fisher, Ronald S. Lipman, E. H. Uhlenhuth, Karl Rickels, Lee C. Park

Research output: Contribution to journalArticlepeer-review

28 Scopus citations


A recurring question appearing in clinical psychopharmacological research concerns the nature of the relationship between initial severity of symptomatology and the magnitude of a drug effect. Data are presented to show that, with meprobamate and placebo in neurotic outpatients, the magnitude of the pharmacological effect remains constant across all levels of initial severity.

Original languageEnglish (US)
Pages (from-to)57-60
Number of pages4
Issue number1
StatePublished - Jan 1965

ASJC Scopus subject areas

  • Pharmacology


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