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Do ketone bodies mediate the anti-seizure effects of the ketogenic diet?
Timothy A. Simeone
, Kristina A. Simeone
,
Carl E. Stafstrom
, Jong M. Rho
School of Medicine
Research output
:
Contribution to journal
›
Review article
›
peer-review
42
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Scopus citations
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Keyphrases
Ketogenic Diet
100%
Ketone Bodies
100%
Antiseizure Effect
100%
β-hydroxybutyrate
60%
Immune Cells
20%
Histone Deacetylases
20%
Blood Levels
20%
Metabolic Enzymes
20%
Seizure Control
20%
Cellular Changes
20%
Fatty Acid Oxidation
20%
Hydroxycarboxylic Acid Receptor 2 (HCAR2)
20%
High-fat Diet
20%
Acetone
20%
Acetoacetate
20%
Molecular Changes
20%
Clinical Effect
20%
Intermediary Metabolism
20%
Neuroprotective Properties
20%
NLRP3 Inflammasome
20%
Biochemical Changes
20%
Hyperexcitability
20%
Metabolic Substrates
20%
Hypersynchrony
20%
Traditional Beliefs
20%
Antiseizure
20%
Anti-seizure Property
20%
Novel Molecular Targets
20%
Neuroscience
Ketogenic Diet
100%
Ketone Bodies
100%
Metabolic Pathway
20%
Neuroprotective Agent
20%
Fatty Acids
20%
Enzymes
20%
Histone Deacetylase
20%
Inflammasome
20%
Receptor
20%
NLRP3
20%
Pharmacology, Toxicology and Pharmaceutical Science
Ketone Bodies
100%
Hydroxybutyric Acid
60%
Receptor
20%
Neuroprotective Agent
20%
Fatty Acid
20%
Molecular Target
20%
Acetoacetic Acid
20%
Histone Deacetylase
20%
Enzymes
20%
Inflammasome
20%
Acetone
20%
Biochemistry, Genetics and Molecular Biology
Ketone Body
100%
Enzyme
20%
Blood Level
20%
Histone Deacetylase
20%
Metabolic Pathway
20%
Mediator
20%
Beta Oxidation
20%
Immunocompetent Cell
20%
NLRP3 Inflammasome
20%
Acetone
20%