DNA Replication: Making Two Forks from One Prereplication Complex

Michael Botchan, James Berger

Research output: Contribution to journalShort surveypeer-review

18 Scopus citations


The copying of chromosomal DNA initiates from a single nucleoprotein assembly called the prereplication complex. New findings in a recent issue of Molecular Cell (Yardimci et al., 2010) reveal that this complex dissolves into two independent replisomes that move away from each other as DNA synthesis ensues.

Original languageEnglish (US)
Pages (from-to)860-861
Number of pages2
JournalMolecular cell
Issue number6
StatePublished - Dec 22 2010
Externally publishedYes

ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology


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